Cavernous angioma surgery: Difference between revisions

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{{CMG}}; {{AE}} [[User:Edzelco|Edzel Lorraine Co, D.M.D., M.D.]]
__NOTOC__
__NOTOC__
{{Cavernous angioma}}
{{Cavernous angioma}}
 
{{CMG}}; {{AE}} [[User:Edzelco|Edzel Lorraine Co, D.M.D., M.D.]]
==Overview==
==Overview==
[[Surgery]] is the mainstay [[treatment]] for [[cavernous angioma]]. [[Complete surgical resection]] should be done to prevent [[seizures]] and [[hemorrhage]] due to remnant [[tissue]].<br />
[[Surgery]] is the mainstay [[treatment]] for [[cavernous angioma]]. [[Complete surgical resection]] should be done to prevent [[seizures]] and [[hemorrhage]] due to remnant [[tissue]].<br />
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==Indication==
==Indication==


*progressive neurologic deficit
*[[Progressive neurologic deficit]]
*recurrent hemorrhage
*[[Recurrent hemorrhage]]
*intractable epilepsy<br />
*Intractable [[epilepsy]]<br />


==Surgery==
==Surgery==


*[[Surgical resection]] is the most preferred intervention for cavernous angioma.
*[[Surgical resection]] is the most preferred [[intervention]] for [[cavernous angioma]].
*[[Complete resection]] is needed as remnant tissue can cause high risk of seizure and hemorrhage.<ref name="pmid29535273">{{cite journal| author=Stapleton CJ, Barker FG| title=Cranial Cavernous Malformations: Natural History and Treatment. | journal=Stroke | year= 2018 | volume= 49 | issue= 4 | pages= 1029-1035 | pmid=29535273 | doi=10.1161/STROKEAHA.117.017074 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29535273  }} </ref>
*[[Complete resection]] is needed as remnant [[tissue]] can cause [[high risk]] of [[seizure]] and [[hemorrhage]].<ref name="pmid29535273">{{cite journal| author=Stapleton CJ, Barker FG| title=Cranial Cavernous Malformations: Natural History and Treatment. | journal=Stroke | year= 2018 | volume= 49 | issue= 4 | pages= 1029-1035 | pmid=29535273 | doi=10.1161/STROKEAHA.117.017074 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29535273  }} </ref>
*Factors that complicate procedure include:
*Factors that complicate procedure include:
**presence of [[gliosis]]
**Presence of [[gliosis]]
**[[calcification]]
**[[Calcification]]
**hyaline degeneration <ref name="pmid12826334">{{cite journal| author=Wang CC, Liu A, Zhang JT, Sun B, Zhao YL| title=Surgical management of brain-stem cavernous malformations: report of 137 cases. | journal=Surg Neurol | year= 2003 | volume= 59 | issue= 6 | pages= 444-54; discussion 454 | pmid=12826334 | doi=10.1016/s0090-3019(03)00187-3 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12826334  }} </ref>
**[[Hyaline degeneration]] <ref name="pmid12826334">{{cite journal| author=Wang CC, Liu A, Zhang JT, Sun B, Zhao YL| title=Surgical management of brain-stem cavernous malformations: report of 137 cases. | journal=Surg Neurol | year= 2003 | volume= 59 | issue= 6 | pages= 444-54; discussion 454 | pmid=12826334 | doi=10.1016/s0090-3019(03)00187-3 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12826334  }} </ref>
*If seizure surgery occurs, hemosiderin ring should be removed.<ref name="pmid18754072">{{cite journal| author=Cenzato M, Stefini R, Ambrosi C, Giovanelli M| title=Post-operative remnants of brainstem cavernomas: incidence, risk factors and management. | journal=Acta Neurochir (Wien) | year= 2008 | volume= 150 | issue= 9 | pages= 879-86; discussion 887 | pmid=18754072 | doi=10.1007/s00701-008-0008-4 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18754072  }} </ref>
*If [[seizure surgery]] occurs, the [[hemosiderin ring]] should be removed.<ref name="pmid18754072">{{cite journal| author=Cenzato M, Stefini R, Ambrosi C, Giovanelli M| title=Post-operative remnants of brainstem cavernomas: incidence, risk factors and management. | journal=Acta Neurochir (Wien) | year= 2008 | volume= 150 | issue= 9 | pages= 879-86; discussion 887 | pmid=18754072 | doi=10.1007/s00701-008-0008-4 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18754072  }} </ref>
*
*


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[[Category:Genetic disorders]]
[[Category:Genetic disorders]]
[[Category:Dermatology]]
[[Category:Dermatology]]
[[Category:Needs content]]
[[Category:Up to Date]]

Latest revision as of 13:07, 12 May 2022

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Edzel Lorraine Co, D.M.D., M.D.

Overview

Surgery is the mainstay treatment for cavernous angioma. Complete surgical resection should be done to prevent seizures and hemorrhage due to remnant tissue.

Indication

Surgery

References

  1. Stapleton CJ, Barker FG (2018). "Cranial Cavernous Malformations: Natural History and Treatment". Stroke. 49 (4): 1029–1035. doi:10.1161/STROKEAHA.117.017074. PMID 29535273.
  2. Wang CC, Liu A, Zhang JT, Sun B, Zhao YL (2003). "Surgical management of brain-stem cavernous malformations: report of 137 cases". Surg Neurol. 59 (6): 444–54, discussion 454. doi:10.1016/s0090-3019(03)00187-3. PMID 12826334.
  3. Cenzato M, Stefini R, Ambrosi C, Giovanelli M (2008). "Post-operative remnants of brainstem cavernomas: incidence, risk factors and management". Acta Neurochir (Wien). 150 (9): 879–86, discussion 887. doi:10.1007/s00701-008-0008-4. PMID 18754072.