Amyotrophic lateral sclerosis history and symptoms: Difference between revisions
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{{Amyotrophic lateral sclerosis}} | {{Amyotrophic lateral sclerosis}} | ||
{{CMG}}{{AE}}{{MMJ}} | |||
==Overview== | ==Overview== | ||
The onset of ALS may be so subtle that the [[symptom]]s are frequently overlooked. The earliest | The onset of ALS may be so subtle that the [[symptom]]s are frequently overlooked. The earliest LMN [[symptom]]s are weakness due to muscle atrophy. This is followed by twitching, cramping, or stiffness of affected muscles; muscle weakness affecting an arm or a leg; and/or slurred and nasal speech. The twitching, cramping, etc. associated with ALS is a result of the dying muscle, due to denervation and sometimes probable re-innervation. | ||
==Symptoms== | == History and Symptoms== | ||
*Weakness | ===History=== | ||
* | ALS is a neurodegenerative disease that ultimately leads to paralysis. Patients may have a positive history of: | ||
*[[Weakness]] start proximally/ distally in upper or lower limbs. | |||
*Stiffness | *[[Twitching]] | ||
* | *[[Cramping]] | ||
*Gradually [[Stiffness]] also develop in affected muscles | |||
*Difficulty swallowing/ speech. | |||
*Drooling | |||
===Symptoms=== | |||
Common symptoms of ALS include: | |||
*[[Muscle weakness]] | |||
*[[Muscle stiffness]] | |||
*[[Gait disturbances]] | |||
*Dysarthria/ dysphagia with bulbar-onset ALS. | |||
*Respiratory difficulties | |||
<ref name="pmid19192301">{{cite journal| author=Wijesekera LC, Leigh PN| title=Amyotrophic lateral sclerosis. | journal=Orphanet J Rare Dis | year= 2009 | volume= 4 | issue= | pages= 3 | pmid=19192301 | doi=10.1186/1750-1172-4-3 | pmc=2656493 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19192301 }} </ref> | |||
==References== | ==References== | ||
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{{WS}} | {{WS}} | ||
[[Category: | |||
[[Category:Motor neuron disease]] | |||
[[Category:Neurology]] | |||
[[Category:Disease]] | |||
Latest revision as of 17:42, 15 September 2021
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]
Overview
The onset of ALS may be so subtle that the symptoms are frequently overlooked. The earliest LMN symptoms are weakness due to muscle atrophy. This is followed by twitching, cramping, or stiffness of affected muscles; muscle weakness affecting an arm or a leg; and/or slurred and nasal speech. The twitching, cramping, etc. associated with ALS is a result of the dying muscle, due to denervation and sometimes probable re-innervation.
History and Symptoms
History
ALS is a neurodegenerative disease that ultimately leads to paralysis. Patients may have a positive history of:
- Weakness start proximally/ distally in upper or lower limbs.
- Twitching
- Cramping
- Gradually Stiffness also develop in affected muscles
- Difficulty swallowing/ speech.
- Drooling
Symptoms
Common symptoms of ALS include:
- Muscle weakness
- Muscle stiffness
- Gait disturbances
- Dysarthria/ dysphagia with bulbar-onset ALS.
- Respiratory difficulties
References
- ↑ Wijesekera LC, Leigh PN (2009). "Amyotrophic lateral sclerosis". Orphanet J Rare Dis. 4: 3. doi:10.1186/1750-1172-4-3. PMC 2656493. PMID 19192301.