Vertigo medical therapy: Difference between revisions

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{{CMG}} {{AE}} {{ZMalik}}
{{CMG}} {{AE}} {{ZMalik}}


==Overview==
Single drug therapy is usually not effective to minimize the [[symptom]], a combination of [[antihistamine]] and [[antiemetic]] are used to control vertigo. Definitive therapy is treating the underlying cause of vertigo.
==Medical Therapy==
*[[Acute]]/severe attacks of vertigo usually subsides in a day or two after brainstem compensation.<ref name="pmid18523693">{{cite journal| author=Kuo CH, Pang L, Chang R| title=Vertigo - part 2 - management in general practice. | journal=Aust Fam Physician | year= 2008 | volume= 37 | issue= 6 | pages= 409-13 | pmid=18523693 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18523693  }} </ref>
*Supportive therapy includes bed rest, [[antihistamine]], [[antiemetic]] ([[prochlorperazine]], [[metoclopramide]]), [[benzodiazepines]] ([[diazepam]],[[lorazepam]]) to relief the [[symptom]].
*[[Meclizine]] is the common [[antihistamine]] used and is safe in [[pregnancy]]. Other [[antihistamines]] used are [[betahistine]] and [[dimenhydrinate]].<ref> Khilnani, AK; Thaddanee, R; Khilnani, G (July 2013). "Anti vertigo drugs-Revisited". National Journal of Integrated Research in Medicine. 4 (4): 118–28.</ref>
*[[Scopolamine]] ([[hyoscine hydrobromide]]) is a common [[anticholinergic]] used to treat the symptom.<ref> Khilnani, AK; Thaddanee, R; Khilnani, G (July 2013). "Anti vertigo drugs-Revisited". National Journal of Integrated Research in Medicine. 4 (4): 118–28.</ref>
*Due to the [[sedative]] effect of these drugs they should be used carefully in the elderly.
*These drugs should not be used for a long period of time as it may delay the compensatory mechanism in the [[brainstem]] and result in the prolongation of vertigo [[symptom]].
*Some patients may be a candidate for [[vestibular]] [[rehabilitation]], it improves balance and decreases [[dizziness]] by exercises that stabilize [[gait]] and [[gaze]].
==Treatment for Common Causes of Vertigo==
:*  
:*  
{| class="wikitable"
{| class="wikitable"
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*Observe if the [[tumor]] is small, [[asymptomatic]], not growing, or in elderly with comorbidities.
*Observe if the [[tumor]] is small, [[asymptomatic]], not growing, or in elderly with comorbidities.
*For large, [[symptomatic]], growing [[tumor]] one of the following treatment is helpful after weighing risks and benefits:  
*For large, [[symptomatic]], growing [[tumor]] one of the following treatment is helpful after weighing risks and benefits:  
**[[Radiationtherapy]]
**[[Radiotherapy]]
**[[Radiosurgery]]
**[[Radiosurgery]]
**Surgical removal   
**Surgical removal   
|-
|-
![[Benign positional paroxysmal vertigo]]
![[Benign paroxysmal positional vertigo]]
|
|
*Effective [[maneuvers]]:[[Epley maneuver]], [[Semont maneuver]], [[Brandt–Daroff exercises]], [[Roll maneuver]].<ref>{{cite journal|doi=10.1002/14651858.CD003162.}}</ref>
*Effective [[maneuvers]]:[[Epley maneuver]], [[Semont maneuver]], [[Brandt–Daroff exercises]], [[Roll maneuver]].<ref>{{cite journal|journal=Cochrane Database of Systematic Reviews|issn=14651858</ref>
*Medical: [[Antihistamine]]([[meclizine]]) and [[anticholinergic]]([[scopolamine]]).<ref>"Meclizine Hydrochloride Monograph for Professionals". American Society of Health-System Pharmacists. Retrieved 22 March 2019</ref>
*Medical: [[Antihistamine]]([[meclizine]]) and [[anticholinergic]]([[scopolamine]]).<ref>"Meclizine Hydrochloride Monograph for Professionals". American Society of Health-System Pharmacists. Retrieved 22 March 2019</ref>
*Surgical: For [[resistant]] and severe cases [[occlusion]] of [[semi-circular canal]] may be helpful.
*Surgical: For [[resistant]] and severe cases [[occlusion]] of [[semi-circular canal]] may be helpful.
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![[Cholesteatoma]]
![[Cholesteatoma]]
|
|
*
*Surgical removal followed by periodic follow-ups.
|-
|-
![[Otosclerosis]]
![[Otosclerosis]]
|
|
*
*Medical: [[Sodium]] [[flouride]] can slow the progression. <ref name="de Oliveira Penidode Oliveira Vicente2018">{{cite journal|last1=de Oliveira Penido|first1=Norma|last2=de Oliveira Vicente|first2=Andy|title=Medical Management of Otosclerosis|journal=Otolaryngologic Clinics of North America|volume=51|issue=2|year=2018|pages=441–452|issn=00306665|doi=10.1016/j.otc.2017.11.006}}</ref>
|-
*Surgical procedure of choice is [[stapedectomy]].<ref name="pmid24303446">{{cite journal| author=Mahafza T, Al-Layla A, Tawalbeh M, Abu-Yagoub Y, Atwan Sulaiman A| title=Surgical Treatment of Otosclerosis: Eight years' Experience at the Jordan University Hospital. | journal=Iran J Otorhinolaryngol | year= 2013 | volume= 25 | issue= 73 | pages= 233-8 | pmid=24303446 | doi= | pmc=3846245 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24303446  }} </ref>
![[Perilymphatic fistula]]
|
*
|+
|+
! colspan="2" |Treating Central Vertigo
! colspan="2" |Treating Central Vertigo
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![[Brainstem]] [[Stroke]]
![[Brainstem]] [[Stroke]]
|
|
*  
* Folow stroke management protocol.
|-
|-
![[Vestibular]] [[Migraine]]
![[Vestibular]] [[Migraine]]
|
|
*
*[[Antiemetic]] coupled with medicines that relieve symptomatic vertigo.<ref name="Sargent2013">{{cite journal|last1=Sargent|first1=Eric W.|title=The challenge of vestibular migraine|journal=Current Opinion in Otolaryngology & Head and Neck Surgery|volume=21|issue=5|year=2013|pages=473–479|issn=1068-9508|doi=10.1097/MOO.0b013e3283648682}}</ref>
|-
|-
![[Multiple Sclerosis]]
![[Multiple Sclerosis]]
|
|
*
*Disease-modifying drugs such as [[glatiramer acetate]], [[interferon-beta]], [[natalizumab]], [[mitoxantrone]] are effective in treat relapsing-remitting type.
|-
*For the secondary progressive, progressive-relapsing, and primary progressive type disease-modifying drugs are less effective.
![[Cerebellar]] [[tumors]]
*Acute relapses are managed by treating the triggering cause, symptomatic therapy, [[corticosteroids]], and/or [[rehabilitation]].
|
*
|-
|-
![[Lateral medullary syndrome]]
![[Cerebellopontine angle]] [[tumors]]
|
|
*
*Observation, [[radiotherapy]], or [[microsurgery]] is selected as a plan of treatment after assessing the size/growth of the [[tumor]], age of the patient, and [[comorbidities]].<ref name="HuangVermeulen2003">{{cite journal|last1=Huang|first1=May Y|last2=Vermeulen|first2=Sandra|title=Clinical perspectives regarding patients with internal auditory canal or cerebellopontine angle lesions: Surgical and radiation oncology perspectives|journal=Seminars in Ultrasound, CT and MRI|volume=24|issue=3|year=2003|pages=124–132|issn=08872171|doi=10.1016/S0887-2171(03)90034-5}}</ref>
|}
|}
==Reference==
{{Reflist|2}}
{{WH}}
{{WS}}

Latest revision as of 16:23, 11 January 2021

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Zehra Malik, M.B.B.S[2]

Overview

Single drug therapy is usually not effective to minimize the symptom, a combination of antihistamine and antiemetic are used to control vertigo. Definitive therapy is treating the underlying cause of vertigo.

Medical Therapy

Treatment for Common Causes of Vertigo

Treating Peripheral Vertigo
Ménière’s disease
Acoustic neuroma
Benign paroxysmal positional vertigo
Acute labyrinthitis
Acute vestibular neuritis
Cholesteatoma
  • Surgical removal followed by periodic follow-ups.
Otosclerosis
Treating Central Vertigo
Brainstem Stroke
  • Folow stroke management protocol.
Vestibular Migraine
  • Antiemetic coupled with medicines that relieve symptomatic vertigo.[14]
Multiple Sclerosis
Cerebellopontine angle tumors

Reference

  1. Kuo CH, Pang L, Chang R (2008). "Vertigo - part 2 - management in general practice". Aust Fam Physician. 37 (6): 409–13. PMID 18523693.
  2. Khilnani, AK; Thaddanee, R; Khilnani, G (July 2013). "Anti vertigo drugs-Revisited". National Journal of Integrated Research in Medicine. 4 (4): 118–28.
  3. Khilnani, AK; Thaddanee, R; Khilnani, G (July 2013). "Anti vertigo drugs-Revisited". National Journal of Integrated Research in Medicine. 4 (4): 118–28.
  4. Phillips, John S; Westerberg, Brian (2011). "Intratympanic steroids for Ménière's disease or syndrome". Cochrane Database of Systematic Reviews. doi:10.1002/14651858.CD008514.pub2. ISSN 1465-1858.
  5. Postema, Rolf J.; Kingma, Charlotte M.; Wit, Hero P.; Albers, Frans W.J.; Van Der Laan, Bernard F.A.M. (2009). "Intratympanic gentamicin therapy for control of vertigo in unilateral Menière's disease: a prospective, double-blind, randomized, placebo-controlled trial". Acta Oto-Laryngologica. 128 (8): 876–880. doi:10.1080/00016480701762458. ISSN 0001-6489.
  6. Syed, I.; Aldren, C. (2012). "Meniere's disease: an evidence based approach to assessment and management". International Journal of Clinical Practice. 66 (2): 166–170. doi:10.1111/j.1742-1241.2011.02842.x. ISSN 1368-5031.
  7. {{cite journal|journal=Cochrane Database of Systematic Reviews|issn=14651858
  8. "Meclizine Hydrochloride Monograph for Professionals". American Society of Health-System Pharmacists. Retrieved 22 March 2019
  9. Seemungal, B M; Bronstein, A M (2008). "A practical approach to acute vertigo". Practical Neurology. 8 (4): 211–221. doi:10.1136/jnnp.2008.154799. ISSN 1474-7758.
  10. Muncie HL, Sirmans SM, James E (2017). "Dizziness: Approach to Evaluation and Management". Am Fam Physician. 95 (3): 154–162. PMID 28145669.
  11. Fishman, Jonathan M; Burgess, Chris; Waddell, Angus (2011). "Corticosteroids for the treatment of idiopathic acute vestibular dysfunction (vestibular neuritis)". Cochrane Database of Systematic Reviews. doi:10.1002/14651858.CD008607.pub2. ISSN 1465-1858.
  12. de Oliveira Penido, Norma; de Oliveira Vicente, Andy (2018). "Medical Management of Otosclerosis". Otolaryngologic Clinics of North America. 51 (2): 441–452. doi:10.1016/j.otc.2017.11.006. ISSN 0030-6665.
  13. Mahafza T, Al-Layla A, Tawalbeh M, Abu-Yagoub Y, Atwan Sulaiman A (2013). "Surgical Treatment of Otosclerosis: Eight years' Experience at the Jordan University Hospital". Iran J Otorhinolaryngol. 25 (73): 233–8. PMC 3846245. PMID 24303446.
  14. Sargent, Eric W. (2013). "The challenge of vestibular migraine". Current Opinion in Otolaryngology & Head and Neck Surgery. 21 (5): 473–479. doi:10.1097/MOO.0b013e3283648682. ISSN 1068-9508.
  15. Huang, May Y; Vermeulen, Sandra (2003). "Clinical perspectives regarding patients with internal auditory canal or cerebellopontine angle lesions: Surgical and radiation oncology perspectives". Seminars in Ultrasound, CT and MRI. 24 (3): 124–132. doi:10.1016/S0887-2171(03)90034-5. ISSN 0887-2171.

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