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| ==Screening== | | ==pic== |
| *According to the Endocrine Society and the European Society for Pediatric Endocrinology, screening for congenital hypothyroidism (cretinism) is recommended in all [[neonates]]. Screening is recommended because early detection of cretinism and early treatment will prevent the consequences of the disease which may be [[mental retardation]].<ref name="pmid24446653">{{cite journal| author=Léger J, Olivieri A, Donaldson M, Torresani T, Krude H, van Vliet G et al.| title=European Society for Paediatric Endocrinology consensus guidelines on screening, diagnosis, and management of congenital hypothyroidism. | journal=J Clin Endocrinol Metab | year= 2014 | volume= 99 | issue= 2 | pages= 363-84 | pmid=24446653 | doi=10.1210/jc.2013-1891 | pmc=4207909 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24446653 }}</ref>
| | {| |
| *In a worldwide view of strategies, screening of cretinism is been held in many countries including the United States. The screening helped in detecting the newborn with [[hypothyroidism]]. These cases are around 2000 annually in the united states and 12,000 worldwide.<ref name="pmid24629860">{{cite journal| author=Ford G, LaFranchi SH| title=Screening for congenital hypothyroidism: a worldwide view of strategies. | journal=Best Pract Res Clin Endocrinol Metab | year= 2014 | volume= 28 | issue= 2 | pages= 175-87 | pmid=24629860 | doi=10.1016/j.beem.2013.05.008 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24629860 }}</ref>
| | |[[image:LowKECG.png|thumb|700px|center|An ECG in a person with a potassium level of 1.1 showing the classical ECG changes of ST segment depression, inverted T waves, large U waves, and a slightly prolonged PR interval. By James Heilman, MD - Own work, CC BY-SA 3.0]] |
| *The screening of cretinism can be performed through the following laboratory tests:<ref name="pmid8533594">{{cite journal| author=Asami T, Otabe N, Wakabayashi M, Kikuchi T, Uchiyama M| title=Congenital hypothyroidism with delayed rise in serum TSH missed on newborn screening. | journal=Acta Paediatr Jpn | year= 1995 | volume= 37 | issue= 5 | pages= 634-7 | pmid=8533594 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8533594 }}</ref><ref name="pmid23154158">{{cite journal| author=Büyükgebiz A| title=Newborn screening for congenital hypothyroidism. | journal=J Clin Res Pediatr Endocrinol | year= 2013 | volume= 5 Suppl 1 | issue= | pages= 8-12 | pmid=23154158 | doi=10.4274/jcrpe.845 | pmc=3608007 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23154158 }}</ref>
| | |} |
| **Measuring the level of [[Thyroxine|thyroxine hormone]] (T4) | | <br style="clear:left" /> |
| **[[Blood]] [[TSH]] assay
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| **Both [[thyroxine]] and [[TSH]] levels
| | [[image:LowKECG.png|thumb|700px|right|An ECG in a person with a potassium level of 1.1 showing the classical ECG changes of ST segment depression, inverted T waves, large U waves, and a slightly prolonged PR interval. By James Heilman, MD - Own work, CC BY-SA 3.0]] |
| | <br style="clear:left" /> |
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| | {{#ev:youtube|7TWu0_Gklzo}} |
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| | ==Table== |
| | {| |
| | ! align="center" style="background:#4479BA; color: #FFFFFF;" + |Complications |
| | ! align="center" style="background:#4479BA; color: #FFFFFF;" + |Polymyositis |
| | ! align="center" style="background:#4479BA; color: #FFFFFF;" + |Dermatomyositis |
| | |- |
| | ! align="center" style="background:#DCDCDC;" + |[[Cancer|Malignancy]] |
| | | align="left" style="background:#F5F5F5;" + | |
| | *[[Lung]] |
| | | align="center" style="background:#F5F5F5;" + | |
| | *[[Lung]] |
| | |} |
