Seminoma classification: Difference between revisions
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==Overview== | ==Overview== | ||
Based on the histology, testicular seminoma may be classified into three subtypes: classic, anaplastic, and spermatocytic.<ref name=pathologyoftesticularseminoma1>Pathology of testicular seminoma. Dr Marcin Czarniecki and Dr Andrew Dixon et al. Radiopaedia 2016. http://radiopaedia.org/articles/testicular-seminoma-1. Accessed on February 25, 2016</ref> | |||
==Classification== | ==Classification== | ||
Based on the histology, testicular seminoma may be classified into three subtypes:<ref name=pathologyoftesticularseminoma1>Pathology of testicular seminoma. Dr Marcin Czarniecki and Dr Andrew Dixon et al. Radiopaedia 2016. http://radiopaedia.org/articles/testicular-seminoma-1. Accessed on February 25, 2016</ref> | Based on the histology, testicular seminoma may be classified into three subtypes:<ref name=pathologyoftesticularseminoma1>Pathology of testicular seminoma. Dr Marcin Czarniecki and Dr Andrew Dixon et al. Radiopaedia 2016. http://radiopaedia.org/articles/testicular-seminoma-1. Accessed on February 25, 2016</ref><ref name="pmid21819630">{{cite journal |vauthors=Boujelbene N, Cosinschi A, Boujelbene N, Khanfir K, Bhagwati S, Herrmann E, Mirimanoff RO, Ozsahin M, Zouhair A |title=Pure seminoma: a review and update |journal=Radiat Oncol |volume=6 |issue= |pages=90 |date=August 2011 |pmid=21819630 |doi=10.1186/1748-717X-6-90 |url=}}</ref> | ||
*'''Classic''': 85%, infrequent [[mitoses]], monotonous sheet of large cells with abundant cytoplasm and round hyperchromatic nuclei, prominent nucleoli | *'''Classic''': 85%, infrequent [[mitoses]], monotonous sheet of large cells with abundant cytoplasm and round hyperchromatic nuclei, prominent nucleoli | ||
*'''Anaplastic''': 10%, 3 or more mitotic figures per high-power field | *'''Anaplastic''': 10%, 3 or more mitotic figures per high-power field | ||
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Latest revision as of 22:35, 10 May 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sogand Goudarzi, MD [2]
Overview
Based on the histology, testicular seminoma may be classified into three subtypes: classic, anaplastic, and spermatocytic.[1]
Classification
Based on the histology, testicular seminoma may be classified into three subtypes:[1][2]
- Classic: 85%, infrequent mitoses, monotonous sheet of large cells with abundant cytoplasm and round hyperchromatic nuclei, prominent nucleoli
- Anaplastic: 10%, 3 or more mitotic figures per high-power field
- Spermatocytic: 5%, older male patients above 60 years old, rarely metastasise; well-differentiated with cells resembling secondary spermatids
References
- ↑ 1.0 1.1 Pathology of testicular seminoma. Dr Marcin Czarniecki and Dr Andrew Dixon et al. Radiopaedia 2016. http://radiopaedia.org/articles/testicular-seminoma-1. Accessed on February 25, 2016
- ↑ Boujelbene N, Cosinschi A, Boujelbene N, Khanfir K, Bhagwati S, Herrmann E, Mirimanoff RO, Ozsahin M, Zouhair A (August 2011). "Pure seminoma: a review and update". Radiat Oncol. 6: 90. doi:10.1186/1748-717X-6-90. PMID 21819630.