Hereditary nonpolyposis colorectal cancer laboratory tests: Difference between revisions
No edit summary |
|||
(14 intermediate revisions by 6 users not shown) | |||
Line 1: | Line 1: | ||
{{Hereditary nonpolyposis colorectal cancer}} | {{Hereditary nonpolyposis colorectal cancer}} | ||
{{CMG}}{{AE}}{{MV}} | {{CMG}}{{AE}}{{MV}}{{Akram}} | ||
==Overview== | ==Overview== | ||
CA 125 | [[Medical laboratory|Laboratory]] findings consistent with the [[diagnosis]] of hereditary nonpolyposis colorectal cancer may include positive [[germline]] [[Test|testing]] for hereditary nonpolyposis colorectal cancer [[Gene|genes]] ([[MLH1]], [[MSH2]], [[MSH6]], and [[PMS2]]), positive EPCAM [[gene]] [[test]], and elevated [[serum]] concentration of [[CEA]] and [[CA-125]]. | ||
==Laboratory Findings== | |||
[[Medical laboratory|Laboratory]] findings consistent with the [[diagnosis]] of hereditary nonpolyposis colorectal cancer may include:<ref name="pmid24827900">{{cite journal |vauthors=Lynch HT, Drescher K, Knezetic J, Lanspa S |title=Genetics, biomarkers, hereditary cancer syndrome diagnosis, heterogeneity and treatment: a review |journal=Curr Treat Options Oncol |volume=15 |issue=3 |pages=429–42 |year=2014 |pmid=24827900 |doi=10.1007/s11864-014-0293-5 |url=}}</ref> | |||
:*Positive EPCAM [[gene]] | |||
:*Positive [[germline]] [[Test|testing]] (MMR) for hereditary nonpolyposis colorectal cancer [[Gene|genes]] ([[MLH1]], [[MSH2]], [[MSH6]] and [[PMS2|PMS-2]]) | |||
:*Elevated [[serum]] concentration of [[CEA]] | |||
:*Elevated [[serum]] concentration of [[CA-125]] | |||
==References== | ==References== | ||
{{reflist| | {{reflist|1}} | ||
[[Category:Disease]] | [[Category:Disease]] | ||
[[Category:Types of cancer]] | [[Category:Types of cancer]] | ||
[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
{{WikiDoc Help Menu}} | {{WikiDoc Help Menu}} | ||
{{WikiDoc Sources}} | {{WikiDoc Sources}} | ||
[[Category:Up-To-Date]] | |||
[[Category:Oncology]] | |||
[[Category:Medicine]] | |||
[[Category:Gastroenterology]] | |||
[[Category:Surgery]] |
Latest revision as of 21:18, 29 April 2019
Hereditary Nonpolyposis Colorectal Cancer Microchapters |
Differentiating Hereditary Nonpolyposis Colorectal Cancer from other Diseases |
---|
Diagnosis |
Treatment |
Case Studies |
Hereditary nonpolyposis colorectal cancer laboratory tests On the Web |
American Roentgen Ray Society Images of Hereditary nonpolyposis colorectal cancer laboratory tests |
FDA on Hereditary nonpolyposis colorectal cancer laboratory tests |
CDC on Hereditary nonpolyposis colorectal cancer laboratory tests |
Hereditary nonpolyposis colorectal cancer laboratory tests in the news |
Blogs on Hereditary nonpolyposis colorectal cancer laboratory tests |
Directions to Hospitals Treating Hereditary nonpolyposis colorectal cancer |
Risk calculators and risk factors for Hereditary nonpolyposis colorectal cancer laboratory tests |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]Ali Akram, M.B.B.S.[3]
Overview
Laboratory findings consistent with the diagnosis of hereditary nonpolyposis colorectal cancer may include positive germline testing for hereditary nonpolyposis colorectal cancer genes (MLH1, MSH2, MSH6, and PMS2), positive EPCAM gene test, and elevated serum concentration of CEA and CA-125.
Laboratory Findings
Laboratory findings consistent with the diagnosis of hereditary nonpolyposis colorectal cancer may include:[1]
References
- ↑ Lynch HT, Drescher K, Knezetic J, Lanspa S (2014). "Genetics, biomarkers, hereditary cancer syndrome diagnosis, heterogeneity and treatment: a review". Curr Treat Options Oncol. 15 (3): 429–42. doi:10.1007/s11864-014-0293-5. PMID 24827900.