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| {{Infobox_Disease |
| | #REDIRECT [[Liver mass pathophysiology]] |
| Name = {{PAGENAME}} |
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| DiseasesDB = 33467 |
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| eMedicineSubj = radio |
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| eMedicineTopic = 286 |
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| MeshID = D020518 |
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| '''Focal nodular hyperplasia''' (FNH) is a benign [[tumour]] of the [[liver]] ([[hepatic tumour]]), which is the second most prevalent tumour of the liver (the first is [[hepatic hemangioma]]). It is usually asymptomatic, rarely grows or bleeds, and has no malignant potential. This tumour is often resected because it is difficult to distinguish from [[adenoma#Liver|hepatic adenoma]].
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| Focal nodular hyperplasia's most recognizable gross feature is a central stellate scar seen in 60-70% of cases. Microscopically, a lobular proliferation of bland-appearing hepatocytes with a bile ductular proliferation and malformed vessels within the fibrous scar is the most common pattern. Other patterns include telangiectatic, hyperplastic-adenomatous, and lesions with focal large-cell dysplasia.<ref name=Nguyen>Nguyen et al. Focal Nodular Hyperplasia of the Liver: A Comprehensive Pathologic Study of 305 Lesions and Recognition of New Histologic Forms. Am J Surg Path 1999:23(12); 1441-4.</ref> Rarely, these lesions may be multiple or can occur as part of a syndrome with hemangiomas, epithelioid hemangioendothelioma, hepatic adenomas, fibrolamellar hepatocellular carcinoma, vascular malformations of the brain, meningiomas, and/or astrocytomas.<ref name=Nguyen/>
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| ==Notes==
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| {{Reflist}}
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| ==References==
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| {{refimprove|date=August 2007}}
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| [[Category:Hepatology]]
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| {{disease-stub}}
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