Rheumatoid arthritis epidemiology and demographics: Difference between revisions

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{{Rheumatoid arthritis}}
{{Rheumatoid arthritis}}
{{CMG}}; {{AE}} {{MKK}} {{AN}}
{{CMG}}; {{AE}} {{MKK}}  


==Overview==
==Overview==
The incidence of [[rheumatoid arthritis]] is approximately  40 per 100,000 individuals worldwide. The prevalence of  [[rheumatoid arthritis]] is approximately 1 percent in Caucasians per 100,000 individuals worldwide.The peak onset of the disease is between the age of 50 and 75 year. Women are three times more commonly affected by [[rheumatoid arthritis]] than men. Mortality rate of [[rheumatoid arthritis]] is approximately 10,000 per 100,000 individuals.
==Epidemiology and Demographics==
===Incidence===
*The incidence of [[rheumatoid arthritis]] is approximately  40 per 100,000 individuals worldwide.<ref name="pmid20191579">{{cite journal |author=Myasoedova E, Crowson CS, Kremers HM, Therneau TM, Gabriel SE |title=Is the incidence of rheumatoid arthritis rising?: results from Olmsted County, Minnesota, 1955-2007 |journal=[[Arthritis and Rheumatism]] |volume=62 |issue=6 |pages=1576–82 |year=2010 |month=June |pmid=20191579 |pmc=2929692 |doi=10.1002/art.27425 |url=http://dx.doi.org/10.1002/art.27425 |accessdate=2012-04-25}}</ref>


==Incidence==
===Prevalence===
The overall age- and sex-adjusted annual [[Rheumatoid arthritis]] incidence is 40.9/100,000 population.<ref name="pmid20191579">{{cite journal |author=Myasoedova E, Crowson CS, Kremers HM, Therneau TM, Gabriel SE |title=Is the incidence of rheumatoid arthritis rising?: results from Olmsted County, Minnesota, 1955-2007 |journal=[[Arthritis and Rheumatism]] |volume=62 |issue=6 |pages=1576–82 |year=2010 |month=June |pmid=20191579 |pmc=2929692 |doi=10.1002/art.27425 |url=http://dx.doi.org/10.1002/art.27425 |accessdate=2012-04-25}}</ref>  
*The prevalence of  [[rheumatoid arthritis]] is approximately 1000 Caucasians per 100,000 worldwide.<ref name="pmid2217956">{{cite journal |vauthors=Spector TD |title=Rheumatoid arthritis |journal=Rheum. Dis. Clin. North Am. |volume=16 |issue=3 |pages=513–37 |date=August 1990 |pmid=2217956 |doi= |url=}}</ref><ref name="pmid22179562">{{cite journal |vauthors=Spector TD |title=Rheumatoid arthritis |journal=Rheum. Dis. Clin. North Am. |volume=16 |issue=3 |pages=513–37 |date=August 1990 |pmid=2217956 |doi= |url=}}</ref><ref name="pmid10406405">{{cite journal |vauthors=Peschken CA, Esdaile JM |title=Rheumatic diseases in North America's indigenous peoples |journal=Semin. Arthritis Rheum. |volume=28 |issue=6 |pages=368–91 |date=June 1999 |pmid=10406405 |doi= |url=}}</ref>
==Age==
 
Onset is uncommon under the age of 15 and from then on the incidence rises with age until the age of 80.
===Mortality rate===
==Gender==
*The mortality rate of [[rheumatoid arthritis]] is approximately 10,000 per 100,000 individuals.
*An estimate of 1.3 million adults had [[Rheumatoid arthritis]] in 2007, affecting women two to three times as often as men. The incidence as well as prevalence of RA in women appears to have increased over the last decade.<ref name="pmid18163481">{{cite journal |author=Helmick CG, Felson DT, Lawrence RC, ''et al.'' |title=Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part I |journal=[[Arthritis and Rheumatism]] |volume=58 |issue=1 |pages=15–25 |year=2008 |month=January |pmid=18163481 |doi=10.1002/art.23177 |url=http://dx.doi.org/10.1002/art.23177 |accessdate=2012-04-25}}</ref>
 
*The lifetime risk of RA in adults is 3.6 % for women and 1.7% for men.<ref name="pmid21360492">{{cite journal |author=Crowson CS, Matteson EL, Myasoedova E, ''et al.'' |title=The lifetime risk of adult-onset rheumatoid arthritis and other inflammatory autoimmune rheumatic diseases |journal=[[Arthritis and Rheumatism]] |volume=63 |issue=3 |pages=633–9 |year=2011 |month=March |pmid=21360492 |pmc=3078757 |doi=10.1002/art.30155 |url=http://dx.doi.org/10.1002/art.30155 |accessdate=2012-04-25}}</ref>
===Age===
==Race==
*Patients of all age groups may develop [[rheumatoid arthritis]].
*Some Native American groups have higher prevalence rates (5-6%) and black persons from the Caribbean region have lower prevalence rates. First-degree relatives prevalence rate is 2-3% and disease genetic concordance in [[Twin#Identical twins|monozygotic twins]] is approximately 12-15% compared to 3.5% in [[Dizygotic twins]].<ref name="pmid3820198">{{cite journal |author=Aho K, Koskenvuo M, Tuominen J, Kaprio J |title=Occurrence of rheumatoid arthritis in a nationwide series of twins |journal=[[The Journal of Rheumatology]] |volume=13 |issue=5 |pages=899–902 |year=1986 |month=October |pmid=3820198 |doi= |url= |accessdate=2012-04-25}}</ref>
*The peak onset of the [[disease]] is between the age of 50 and 75 years.
*It is strongly associated with the inherited tissue type [[Major histocompatibility complex]] (MHC) class II antigen [[Human leukocyte antigen|HLA]]-DR4 (most specifically DR0401 and 0404) — hence family history is an important risk factor.<ref name="pmid21125177">{{cite journal |author=Arias MV, Domingues EV, Lozano RB, Flores CV, Peralta MM, Salinas CZ |title=Study of class I and II HLA alleles in 30 ecuadorian patients with rheumatoid arthritis compared with alleles from healthy and affected subjects with other rheumatic diseases |journal=[[Revista Brasileira De Reumatologia]] |volume=50 |issue=4 |pages=423–33 |year=2010 |month=August |pmid=21125177 |doi= |url=http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0482-50042010000400007&lng=en&nrm=iso&tlng=en |accessdate=2012-04-25}}</ref>
 
===Race===
*[[Rheumatoid arthritis]] usually affects Native Americans.
*African Americans  and Caribbean region are less likely to develop rheumatoid arthritis .
===Gender===
*[[Women]] are three times more commonly affected by [[rheumatoid arthritis]] than [[men]].<ref name="pmid10914844">{{cite journal |vauthors=Takagi H, Ishiguro N, Iwata H, Kanamono T |title=Genetic association between rheumatoid arthritis and estrogen receptor microsatellite polymorphism |journal=J. Rheumatol. |volume=27 |issue=7 |pages=1638–42 |date=July 2000 |pmid=10914844 |doi= |url=}}</ref><ref name="pmid18163481">{{cite journal |author=Helmick CG, Felson DT, Lawrence RC, ''et al.'' |title=Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part I |journal=[[Arthritis and Rheumatism]] |volume=58 |issue=1 |pages=15–25 |year=2008 |month=January |pmid=18163481 |doi=10.1002/art.23177 |url=http://dx.doi.org/10.1002/art.23177 |accessdate=2012-04-25}}</ref>


==References==
==References==

Latest revision as of 16:36, 23 April 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Manpreet Kaur, MD [2]

Overview

The incidence of rheumatoid arthritis is approximately 40 per 100,000 individuals worldwide. The prevalence of rheumatoid arthritis is approximately 1 percent in Caucasians per 100,000 individuals worldwide.The peak onset of the disease is between the age of 50 and 75 year. Women are three times more commonly affected by rheumatoid arthritis than men. Mortality rate of rheumatoid arthritis is approximately 10,000 per 100,000 individuals.

Epidemiology and Demographics

Incidence

Prevalence

Mortality rate

Age

Race

  • Rheumatoid arthritis usually affects Native Americans.
  • African Americans and Caribbean region are less likely to develop rheumatoid arthritis .

Gender

References

  1. ↑ Myasoedova E, Crowson CS, Kremers HM, Therneau TM, Gabriel SE (2010). "Is the incidence of rheumatoid arthritis rising?: results from Olmsted County, Minnesota, 1955-2007". Arthritis and Rheumatism. 62 (6): 1576–82. doi:10.1002/art.27425. PMC 2929692. PMID 20191579. Retrieved 2012-04-25. Unknown parameter |month= ignored (help)
  2. ↑ Spector TD (August 1990). "Rheumatoid arthritis". Rheum. Dis. Clin. North Am. 16 (3): 513–37. PMID 2217956.
  3. ↑ Spector TD (August 1990). "Rheumatoid arthritis". Rheum. Dis. Clin. North Am. 16 (3): 513–37. PMID 2217956.
  4. ↑ Peschken CA, Esdaile JM (June 1999). "Rheumatic diseases in North America's indigenous peoples". Semin. Arthritis Rheum. 28 (6): 368–91. PMID 10406405.
  5. ↑ Takagi H, Ishiguro N, Iwata H, Kanamono T (July 2000). "Genetic association between rheumatoid arthritis and estrogen receptor microsatellite polymorphism". J. Rheumatol. 27 (7): 1638–42. PMID 10914844.
  6. ↑ Helmick CG, Felson DT, Lawrence RC; et al. (2008). "Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part I". Arthritis and Rheumatism. 58 (1): 15–25. doi:10.1002/art.23177. PMID 18163481. Retrieved 2012-04-25. Unknown parameter |month= ignored (help)

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