Henoch-Schönlein purpura causes: Difference between revisions
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==Overview== | ==Overview== | ||
The common causes of Henoch-Schönlein purpura (HSP) are [[infections]], [[medications]], [[Hypersesitivity|hypersensitivity]], [[vaccinations]], [[genetics]] etc. | |||
==Causes== | ==Causes== | ||
*The causes of the HSP is as follows:<ref name="pmid25072122">{{cite journal |vauthors=Davin JC, Coppo R |title=Henoch-Schönlein purpura nephritis in children |journal=Nat Rev Nephrol |volume=10 |issue=10 |pages=563–73 |date=October 2014 |pmid=25072122 |doi=10.1038/nrneph.2014.126 |url=}}</ref><ref name="pmid25399937">{{cite journal |vauthors=Micheletti RG, Werth VP |title=Small vessel vasculitis of the skin |journal=Rheum. Dis. Clin. North Am. |volume=41 |issue=1 |pages=21–32, vii |date=2015 |pmid=25399937 |doi=10.1016/j.rdc.2014.09.006 |url=}}</ref><ref name="pmid25306598">{{cite journal |vauthors=Zhdanova LV, Patrushev LI, Dolgikh VV, Bimbaev AB, Khoĭkova OCh |title=[The contribution of genes polymorphism of thrombophilia in clinical variability of hemorrhagic vasculitis] |language=Russian |journal=Vestn. Akad. Med. Nauk SSSR |volume= |issue=3-4 |pages=61–4 |date=2014 |pmid=25306598 |doi= |url=}}</ref><ref name="pmid23684700">{{cite journal |vauthors=Rigante D, Castellazzi L, Bosco A, Esposito S |title=Is there a crossroad between infections, genetics, and Henoch-Schönlein purpura? |journal=Autoimmun Rev |volume=12 |issue=10 |pages=1016–21 |date=August 2013 |pmid=23684700 |doi=10.1016/j.autrev.2013.04.003 |url=}}</ref><ref name="pmid25688001">{{cite journal |vauthors=Audemard-Verger A, Pillebout E, Guillevin L, Thervet E, Terrier B |title=IgA vasculitis (Henoch-Shönlein purpura) in adults: Diagnostic and therapeutic aspects |journal=Autoimmun Rev |volume=14 |issue=7 |pages=579–85 |date=July 2015 |pmid=25688001 |doi=10.1016/j.autrev.2015.02.003 |url=}}</ref><ref name="pmid18524107">{{cite journal |vauthors=Pillebout E, Niaudet P |title=[Henoch-Schönlein purpura] |language=French |journal=Rev Prat |volume=58 |issue=5 |pages=507–11 |date=March 2008 |pmid=18524107 |doi= |url=}}</ref> | |||
*The exact cause of HSP is not clear. | *The exact cause of HSP is not clear. | ||
*'''Common causes''' | |||
* | **[[Infection|Infections]]- | ||
**[[Medications]] | |||
**[[Hypersesitivity|Hypersensitivity]] | |||
**[[Vaccinations]]- certain vaccines can cause HSP such as [[Typhoid]], [[HBV]], [[Measles, Mumps, and Rubella Vaccines|Measles]], [[Yellow fever]], and [[Cholera]]. | |||
*'''Rare causes''' | |||
**[[Genetics]]- very rarely HSP can occur in twins and within the family | |||
**'''Other triggers''' Certain drugs, [[bacteria]], insect bites, viral infections, food, cold weather, and trauma may also cause HSP. | |||
*In HSP, the [[antibodies]] are directed against the [[blood vessels]] causing [[vasculitis]], [[bleeding]] into the skin leading to a subsequent skin rash. | |||
*[[Allergy|Allergic]] reaction to foods may cause HSP. | |||
*Very rarely HSP can occur in twins and within the family.<br> | |||
==References== | ==References== | ||
Latest revision as of 19:51, 15 April 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
The common causes of Henoch-Schönlein purpura (HSP) are infections, medications, hypersensitivity, vaccinations, genetics etc.
Causes
- Common causes
- Infections-
- Medications
- Hypersensitivity
- Vaccinations- certain vaccines can cause HSP such as Typhoid, HBV, Measles, Yellow fever, and Cholera.
- Rare causes
- In HSP, the antibodies are directed against the blood vessels causing vasculitis, bleeding into the skin leading to a subsequent skin rash.
- Allergic reaction to foods may cause HSP.
- Very rarely HSP can occur in twins and within the family.
References
- ↑ Davin JC, Coppo R (October 2014). "Henoch-Schönlein purpura nephritis in children". Nat Rev Nephrol. 10 (10): 563–73. doi:10.1038/nrneph.2014.126. PMID 25072122.
- ↑ Micheletti RG, Werth VP (2015). "Small vessel vasculitis of the skin". Rheum. Dis. Clin. North Am. 41 (1): 21–32, vii. doi:10.1016/j.rdc.2014.09.006. PMID 25399937.
- ↑ Zhdanova LV, Patrushev LI, Dolgikh VV, Bimbaev AB, Khoĭkova O (2014). "[The contribution of genes polymorphism of thrombophilia in clinical variability of hemorrhagic vasculitis]". Vestn. Akad. Med. Nauk SSSR (in Russian) (3–4): 61–4. PMID 25306598. Vancouver style error: initials (help)
- ↑ Rigante D, Castellazzi L, Bosco A, Esposito S (August 2013). "Is there a crossroad between infections, genetics, and Henoch-Schönlein purpura?". Autoimmun Rev. 12 (10): 1016–21. doi:10.1016/j.autrev.2013.04.003. PMID 23684700.
- ↑ Audemard-Verger A, Pillebout E, Guillevin L, Thervet E, Terrier B (July 2015). "IgA vasculitis (Henoch-Shönlein purpura) in adults: Diagnostic and therapeutic aspects". Autoimmun Rev. 14 (7): 579–85. doi:10.1016/j.autrev.2015.02.003. PMID 25688001.
- ↑ Pillebout E, Niaudet P (March 2008). "[Henoch-Schönlein purpura]". Rev Prat (in French). 58 (5): 507–11. PMID 18524107.