Bamifylline: Difference between revisions

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{{chembox
<div style="float: right;">
| Verifiedfields = changed
[[File:Bamifylline.png|thumb|none|400px|This image is provided by the National Library of Medicine.]]</div>
| verifiedrevid = 459517599
__NOTOC__
|ImageFile=Bamifylline.png
{{SI}}
|ImageSize=200px
{{CMG}}
|IUPACName=8-benzyl-7-[2-[ethyl(2-hydroxyethyl)amino]ethyl]-1,3-dimethylpurine-2,6-dione
==Overview==
|OtherNames=
'''Bamifylline''' is a [[drug]] of the [[xanthine]] [[chemical class]] which acts as a [[functional_selectivity|selective]] [[Adenosine receptor|Adenosine receptor A1]]
|Section1={{Chembox Identifiers
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 15401
| InChI = 1/C20H27N5O3/c1-4-24(12-13-26)10-11-25-16(14-15-8-6-5-7-9-15)21-18-17(25)19(27)23(3)20(28)22(18)2/h5-9,26H,4,10-14H2,1-3H3
| InChIKey = VVUYEFBRTFASAH-UHFFFAOYAJ
| CASNo_Ref = {{cascite|changed|??}}
| CASNo=2016-63-9
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 2110760
|  StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C20H27N5O3/c1-4-24(12-13-26)10-11-25-16(14-15-8-6-5-7-9-15)21-18-17(25)19(27)23(3)20(28)22(18)2/h5-9,26H,4,10-14H2,1-3H3
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = VVUYEFBRTFASAH-UHFFFAOYSA-N
| PubChem=16229
| ATCCode_prefix = R03
| ATCCode_suffix = DA08
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = ZTY15D026H
| SMILES = O=C2N(c1nc(n(c1C(=O)N2C)CCN(CC)CCO)Cc3ccccc3)C
}}
|Section2={{Chembox Properties
|  Formula=C<sub>20</sub>H<sub>27</sub>N<sub>5</sub>O<sub>3</sub>
|  MolarMass=385.46008
|  Appearance=
|  Density=
|  MeltingPt=
|  BoilingPt=
|  Solubility=
  }}
|Section3={{Chembox Hazards
|  MainHazards=
|  FlashPt=
|  Autoignition=
  }}
}}
 
'''Bamifylline''' is a [[drug]] of the [[xanthine]] [[chemical class]] which acts as a [[functional_selectivity|selective]] [[Adenosine receptor A1|adenosine A<sub>1</sub> receptor]] [[antagonist (pharmacology)|antagonist]].<ref name="pmid8781823">{{cite journal |author=Tomai F, Crea F, Gaspardone A, Versaci F, De Paulis R, Polisca P, Chiariello L, Gioffrè PA |title=Effects of A1 adenosine receptor blockade by bamiphylline on ischaemic preconditioning during coronary angioplasty |journal=European Heart Journal |volume=17 |issue=6 |pages=846–53 |date=June 1996 |pmid=8781823 |doi= 10.1093/oxfordjournals.eurheartj.a014965|url=}}</ref><ref>{{cite pmid|6752929}}</ref>
 
== See also ==
== See also ==
* [[Theophylline]]
* [[Theophylline]]
Line 49: Line 11:


== References ==
== References ==
{{Reflist}}
{{Reflist|2}}


{{Drugs for obstructive airway diseases}}
{{Drugs for obstructive airway diseases}}
{{Adenosinergics}}
[[Category:Adenosine receptor antagonists]]
[[Category:Xanthines]]
[[Category:Xanthines]]
[[Category:Alcohols]]
[[Category:Alcohols]]
 
[[Category:Drug]]
 
{{respiratory-system-drug-stub}}
{{cardiovascular-drug-stub}}

Latest revision as of 17:54, 18 August 2015

This image is provided by the National Library of Medicine.

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Bamifylline is a drug of the xanthine chemical class which acts as a selective Adenosine receptor A1

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