Zygomycosis history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Zygomycosis frequently involves the sinuses, brain, or lungs as the sites of infection. Whilst orbitorhinocerebral Zygomycosis is the most common type of the disease, this infection can also manifest in the gastrointestinal tract, skin, and in other organ systems.

Common Symptoms

Symptoms of rhinocerebral zygomycosis include:

Symptoms of lung (pulmonary) zygomycosis include:

Symptoms of gastrointestinal zygomycosis include:

Symptoms of kidney (renal) zygomycosis include:

  • Fever
  • Flank (side) pain

Symptoms of skin (cutaneous) zygomycosis include a single, painful, hardened area of skin that may have a blackened center.

Less Common Symptoms

Rarely, maxilla may be affected by Zygomycosis. The lack of case reports regarding maxillofacial Zygomycosis lies in the rich vascularity of the maxillofacial areas preventing fungal infections, although this can be overcome by more prevalent fungi, bacteria or viruses such as those responsible for Zygomycosis.

Basidiobolomycosis is usually a superficial infection of skin, but may very rarely cause lesions of the bowel or liver, mimicking bowel cancer,[1] or Crohn's disease.[2]


  1. Van den berk GEL, Noorduyn LA, van Ketel RJ; et al. (2006). "A fatal pseudo-tumour: disseminated basidiobolomycosis". BMC Infect Dis. 6: 140. doi:10.1186/1471-2334-6-140.
  2. Zavasky DM, Samowitz W, Loftus T, Segal H, Carroll K (1999). "Gastrointestinal zygomycotic infection caused by Basidiobolus ranarum: case report and review". Clin Infect Dis. 28 (6): 1244&ndash, 8.

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