Z12 small nucleolar RNA
Jump to navigation
Jump to search
| Small nucleolar RNA SNORD104 | |
|---|---|
| File:RF00289.jpg Predicted secondary structure and sequence conservation of SNORND104 | |
| Identifiers | |
| Symbol | SNORND104 |
| Alt. Symbols | snoZ12; Z12 |
| Rfam | RF00289 |
| Other data | |
| RNA type | Gene; snRNA; snoRNA; CD-box |
| Domain(s) | Eukaryota |
| GO | 0006396 0005730 |
| SO | 0001263 |
| Locus | Chr. 13 [1] |
| PDB structures | PDBe |
Z12 small nucleolar RNA is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis.[1] It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. Z12 snoRNA belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.[1]
References
- ↑ 1.0 1.1 Galardi, S.; Fatica, A.; Bachi, A.; Scaloni, A.; Presutti, C.; Bozzoni, I. (October 2002). "Purified Box C/D snoRNPs Are Able to Reproduce Site-Specific 2'-O-Methylation of Target RNA in Vitro". Molecular and Cellular Biology. 22 (19): 6663–6668. doi:10.1128/MCB.22.19.6663-6668.2002. PMC 134041. PMID 12215523.
External links
 | This molecular or cell biology article is a stub. You can help Wikipedia by expanding it. |