Von Braun reaction

Jump to navigation Jump to search


The Von Braun reaction is an organic reaction in which a tertiary amine reacts with cyanogen bromide to an organocyanamide [1]. An example is the reaction of dimethyl-α-naphthylamine [2]:

Von Braun reaction

The reaction mechanism consists of two nucleophilic substitutions: the amine is the first nucleophile displacing the bromine atom which then acts as the second nucleophile [3].

See also

References

  1. Von Braun, Heider, and Muller, Ber., 51, 281 (1918).
  2. Organic Syntheses, Coll. Vol. 3, p.608 (1955); Vol. 27, p.56 (1947). http://www.orgsynth.org/orgsyn/pdfs/CV3P0608.pdf
  3. Template:JerryMarch

Template:WS