Valofane

Valofane
	File:Valofane.png
Gene therapy
Clinical data
Other names	Valofan, Valofane
Physiological data
Legal status
Pharmacokinetic data
Identifiers
	IUPAC name N-carbamoyl-5-methyl-2-oxo-3-prop-2-enyloxolane-3-carboxamide;
CAS Number	3258-51-3;
PubChem Template:Abbreviation	71122;
Chemical and physical data
Formula	C10H14N2O4
Molar mass	226.229 g/mol

Valofane is a sedative drug structurally related to the barbiturates^[1] and similar drugs such as primidone. It is metabolised once inside the body to form the barbiturate proxibarbal and is thus a prodrug.^[2]

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References

↑ Traversa U, Puppini P, Jacquot C, Vertua R. Effect of an atypical barbiturate, the 2-allophanyl-2-allyl-4-valerolactone (valofan), on exploratory behaviour and brain serotonin concentrations in mice. Journal de Pharmacologie. 1985 Jul-Sep;16(3):279-90.
↑ Lambrey B, Compagnon PL, Jacquot C. Pharmacokinetics of 14C-2-allophanyl-2-allyl -gamma-valero-lactone: a prodrug of proxibarbal in rats. European Journal of Drug Metabolism and Pharmacokinetics. 1981;6(3):161-9.

Template:Barbiturates Template:WikiDoc Sources

[1] Traversa U, Puppini P, Jacquot C, Vertua R. Effect of an atypical barbiturate, the 2-allophanyl-2-allyl-4-valerolactone (valofan), on exploratory behaviour and brain serotonin concentrations in mice. Journal de Pharmacologie. 1985 Jul-Sep;16(3):279-90.

[2] Lambrey B, Compagnon PL, Jacquot C. Pharmacokinetics of 14C-2-allophanyl-2-allyl -gamma-valero-lactone: a prodrug of proxibarbal in rats. European Journal of Drug Metabolism and Pharmacokinetics. 1981;6(3):161-9.

[1]

[2]

Valofane

References

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