Traveler's diarrhea natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Yazan Daaboul, M.D.; Serge Korjian M.D.

Overview

In the general population, traveler's diarrhea is usually self-limited with an excellent prognosis in the majority of cases. In bacterial and viral traveler's diarrhea, symptoms typically last a few hours to several days after exposure. In protozoal traveler's diarrhea, symptoms may persist for several weeks / months. Complications of traveler's diarrhea are generally related to the dehydration associated with severe diarrhea. Other complications are related to the infectious agent responsible for the disease.

Natural History, Complications and Prognosis

  • In the general population, traveler's diarrhea is usually self-limited with an excellent prognosis in the majority of cases.
  • The following table summarizes, the natural history, complications, and prognosis of the common infectious agents responsible for traveler's diarrhea.
Agent Incubation Period Natural History Common Complications Prognosis in the General Population
Bacteria
E. coli
  • 1 day to 10 days
  • Excellent
Campylobacter jejuni
  • 1 day to 7 days
  • Excellent
Shigella
  • 1 day to 3 days
  • Excellent
Salmonella
  • 6 hrs to 3 days
  • Excellent
Viruses
Norovirus
  • 12 hrs to 2 days
  • Excellent
Rotavirus
  • 12 hrs to 2 days
  • Excellent
Protozoa
Giardia
  • 7 days to 21 days
  • Excellent
Entamoeba histolytica
  • 7 days to 21 days
  • Extraluminal complications common
  • Excellent
Cryptosporidium
  • 2 days to 10 days
  • Excellent

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