Transient global amneisa epidemiology and demographics
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Epidemiology of Transient Global Amnesia
- Each year, approximately 3 to 8 persons per 100,000 population experience an episode of transient global amnesia.
- The condition occurs more frequently in persons older than 50 years of age.
- In a retrospective series of 277 cases, the mean age was 62 years.
- Sex distribution has varied across studies:
- Some series report slightly more men than women,
- Other series show the opposite pattern.
- In most series, about 15% of patients have had more than one episode.
- Among those with recurrent episodes, the average interval between episodes was approximately 2 years, and almost two thirds had three or more definite or probable episodes.
- Estimates of recurrence frequency and intervals vary among studies.
- Data from a retrospective series of 1044 patients suggested that younger age at first episode and a personal or family history of migraine were associated with future episodes, although these findings have not been consistently affirmed.
- Cardiovascular risk factors have been overrepresented in some series but are considered commensurate with the typical age range of affected patients.
- A higher risk of transient global amnesia has been reported among patients with migraine compared with those without migraine.
- Rare reports of transient global amnesia in adolescents have been linked to athletic activity and a history of migraine.