Tiazofurine

Tiazofurine

Clinical data
Synonyms	2-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-thiazole-4-carboxamide
ATC code	L01XX18 (WHO)
Identifiers
IUPAC name (1R)-1-[4-(aminocarbonyl)-1,3-thiazol-2-yl]-1,4-anhydro-D-ribitol
CAS Number	60084-10-8
PubChem CID	457954
ChemSpider	403014 Y
UNII	ULJ82834RE
ChEMBL	ChEMBL108358 Y
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C9H12N2O5S
Molar mass	260.268 g/mol
3D model (JSmol)	Interactive image
SMILES O=C(c1nc(sc1)[C@@H]2O[C@@H]([C@@H](O)[C@H]2O)CO)N
InChI InChI=1S/C9H12N2O5S/c10-8(15)3-2-17-9(11-3)7-6(14)5(13)4(1-12)16-7/h2,4-7,12-14H,1H2,(H2,10,15)/t4-,5-,6-,7-/m1/s1 Y Key:FVRDYQYEVDDKCR-DBRKOABJSA-N Y
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Definitions
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Tiazofurin is an inhibitor of IMP dehydrogenase. Tiazofurin and its analogues are under investigation for potential use in the treatment of cancer.