Template:Antibiotic treatment

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vishnu Vardhan Serla M.B.B.S. [2], Rim Halaby

Overview

In this section, try to provide a brief overview of the treatment plan where you summarize the whole treatment approach.

An example:

"When a patient presents with suspicion of meningitis, the antibiotics treatment should be started as soon as possible no longer than 30 minutes after the presentation of the patient. An empiric treatment is started without waiting for the results of the blood and spinal fluid cultures. Once the results of the cultures are out, the antibiotics regimen is adjusted in terms of type and dose depending on the specific nature of the pathogen."

Medical Therapy

• At the beginning of this section, provide a more elaborate description of the treatment without mentioning the details that will be provided in the following table.
• Then create a table similar to the one provided below. Make sure to put a title for the table.

• Sometimes the treatment is divided into several categories. In that case, create a subheading for each subtype, and by that we mean the title is surrounded by " === ".
  • For example: Treatment of meningitis:
    • 1- Empiric treatment (Put this subheading between "===")
    • 2- Specific treatment (Put this subheading between "===")
  • Another example: Treatment of endocarditis:
    • 1- Treatment of native valve endocarditis (Put this subheading between "===")
    • 2- Treatment of prosthetic valve endocarditis (Put this subheading between "===")

For example:

Empiric Treatment

• Do not wait for the results of the CT scan and the lumbar puncture; empiric treatment should be started as soon as possible.
• Blood cultures should be drawn before starting the antibiotic therapy, and then the antibiotic treatment should be changed once the blood culture results are out.
• Empiric antibiotic treatment should be started within 30 minutes after the patient presentation.
• In case of high suspicion of pneumococcal meningitis in adult patients, 0.15 mg/kg IV Q6H dexomethasone should be administered for 2 to 4 days.
  • The first dose of dexomethasone is given along with or 20 minutes prior to starting the antibiotics treatment.

Shown below is a table summarizing the preferred and alternative empiric treatment for meningitis.

Possible Pathogens	Optimal Treatment	Duration of Treatment	Alternative Treatment
Streptococcus pneumonia Nisseria meningitis Hemophilus influenzae	Vancomycin Loading dose:25-35 mg/kg, then 15-20 mg/kg Q8-12H Trough concentration: 20mcg/mL + Ceftriaxone 2 g IV Q12H	Stop or adjust treatment choice and duration when the results of the lumbar puncture are out	In case of penicillin allergy: Chloramphenicol + Vancomycin
Pathogen 1 Pathogen 2 Pathogen 3	Antibiotic 1 Dosage of antibiotic 1 OR Antibiotic 2 Dosage of antibiotic 2	Duration of row 2	In case of allergy of X, or in case of failure of treatment (row 2) Antibiotic a Dosage of antibiotic a + Antibiotic b Dosage of antibiotic b
Pathogen 4 Pathogen 5	Antibiotic 3 Dosage of antibiotic 3 OR Antibiotic 4 Dosage of antibiotic 4	Duration of row 3	In case of allergy of X, or in case of failure of treatment (row 3) Antibiotic c Dosage of antibiotic c + Antibiotic d Dosage of antibiotic d
Pathogen 6 Pathogen 7 Pathogen 8	Antibiotic 5 Dosage of antibiotic 5	Duration of row 4	In case of allergy of X, or in case of failure of treatment (row 4) Antibiotic e Dosage of antibiotic e + Antibiotic f Dosage of antibiotic f

• In the table, make sure that the words in the first row AND the first column are in bold.
• In the column that contains preferred treatment, make sure the name of the antibiotics (without the dosing) are in bold.

• For further examples, visit the page: http://www.wikidoc.org/index.php/Meningitis_medical_therapy

References

Don't forget to reference your work!