Swainsonine

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Overview

Swainsonine is a potent inhibitor of Golgi alpha-mannosidase II, immunomodulator and potential anticancer agent. Disruption of Golgi alpha-mannosidase II with swainsonine induces hybrid-type glycans. These glycans have a Man5GlcNAc2 core with processing on the 3-arm that resembles so-called complex-type glycans.

The pharmacological properties of this product have not been fully investigated.

Handling Instructions

• Soluble in water (10 mg/1 ml) and ethanol
• Use caution when handling.
• This product must not be used in humans
• Store between 0-4 ˚C for up to 1 year
• Store or 20 ˚C for up to 3 months
• Disposal: A

References

• Swainsonine at Logan Natural Products