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The structure and bonding of the sulfate ion

A sulfotransferase is a transferase enzyme which acts upon a sulfate group.[1] These enzymes often act to transfer a sulfate group from the coenzyme 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) to a second substrate such as a protein or lipid.[2]

They are classified under EC number 2.8.2.

An example is SULT2A1.

See also


  1. Negishi M, Pedersen LG, Petrotchenko E; et al. (2001). "Structure and function of sulfotransferases". Arch. Biochem. Biophys. 390 (2): 149–57. PMID 11396917.
  2. Rath VL, Verdugo D, Hemmerich S (2004). "Sulfotransferase structural biology and inhibitor discovery". Drug Discov. Today. 9 (23): 1003–11. PMID 15574316.

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