Splenic vein thrombosis differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Vindhya BellamKonda, M.B.B.S [2]

Overview

Splenic vein thrombosis must be differentiated from hepatic vein thrombosis, portal vein thrombosis, testicular cancer, hyperhomocystenemia, and deep vein thrombosis.

Differential diagnosis

Splenic vein thrombosis (SVT) must be differentiated from hepatic vein thrombosis (HVT), portal vein thrombosis (PVT), testicular cancer, hyperhomocystenemia, and deep vein thrombosis.[1][2][3]

Disease Abdominal pain Leg swelling Portal HTN Rectal bleeding CT abdomen Doppler US of deep viens Urine chemistry
SVT Present Absent Present Present Thrombosis in SV Normal Normal
HVT Present Absent Present Present Thrombosis in HV Normal Normal
Hyperhomocystenemia Present Absent Present if PVT Present if PVT No specific finding May have thrombosis if deep veins involved Elevated homocysteine
DVT Present Present Absent Absent No specific Thrombosis in deep veins Normal
PVT Present Absent Present Present Thrombosis in PV Normal Normal

References

  1. ↑ Venkatesh P, Shaikh N, Malmstrom MF, Kumar VR, Nour B (2014). "Portal, superior mesenteric and splenic vein thrombosis secondary to hyperhomocysteinemia with pernicious anemia: a case report". J Med Case Rep. 8: 286. doi:10.1186/1752-1947-8-286. PMC 4154050. PMID 25155131.
  2. ↑ Salazar-Mejía CE, Hernández-Barajas D, Llerena-Hernández E, González-Vela JL, Contreras-Salcido MI, González-Gutiérrez A, Borjas-Almaguer OD, Pérez-Arredondo LA, Wimer-Castillo BO (2017). "Testicular Cancer Presenting as Gastric Variceal Hemorrhage". Case Rep Gastrointest Med. 2017: 4510387. doi:10.1155/2017/4510387. PMC 5695022. PMID 29234547.
  3. ↑ Bertrand A, Heissat S, Caron N, Viremouneix L, Pracros JP, Javouhey E, Lachaux A, Mialou V (2014). "[Deep vein thrombosis revealing myeloproliferative syndrome in two adolescents]". Arch Pediatr (in French). 21 (5): 497–500. doi:10.1016/j.arcped.2014.02.019. PMID 24709317.
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