Spina bifida surgery

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]

Overview

The management of open spina bifida is surgery within 48 h of birth. The defect in the spine is closed to minimize the risk of ascending infection that can result in meningitis. Prenatal surgery is the preferred treatment for spina bifida and it usually is done before the 26th week of pregnancy and it may prevent continuing damage and improve clinical outcome. Intrauterine repair of spina bifida confers multiple advantages to infants, including: Lower rates of shunt dependency, lower rates of hindbrain herniation and better motor and disability functional outcomes. Surgery after birth is done in patients who did not underwent prenatal surgery but the prognosis is worse and there are more possible complications after surgery in comparison with the prenatal surgery. The management of open spina bifida is surgery within 48 h of birth. The defect in the spine is closed to minimize the risk of ascending infection that can result in meningitis. Prenatal surgery is the preferred treatment for spina bifida and it usually is done before the 26th week of pregnancy and it may prevent continuing damage and improve clinical outcome. Intrauterine repair of spina bifida confers multiple advantages to infants, including: Lower rates of shunt dependency, lower rates of hindbrain herniation and better motor and disability functional outcomes. Surgery after birth is done in patients who did not underwent prenatal surgery but the prognosis is worse and there are more possible complications after surgery in comparison with the prenatal surgery.

Indications

The management of open spina bifida is surgery within 48 h of birth. The defect in the spine is closed to minimize the risk of ascending infection that can result in meningitis. Prenatal surgery is the preferred treatment for spina bifida and it usually is done before the 26th week of pregnancy and it may prevent continuing damage and improve clinical outcome. Intrauterine repair of spina bifida confers multiple advantages to infants, including: Lower rates of shunt dependency, lower rates of hindbrain herniation and better motor and disability functional outcomes. Surgery after birth is done in patients who did not underwent prenatal surgery but the prognosis is worse and there are more possible complications after surgery in comparison with the prenatal surgery.

Surgery

  • The management of open spina bifida is surgery within 48 h of birth.
  • The defect in the spine is closed to minimize the risk of ascending infection that can result in meningitis.
  • Prenatal surgery is the preferred treatment for spina bifida and it usually is done before the 26th week of pregnancy and it may prevent continuing damage and improve clinical outcome. [1][2][3]
  • Intrauterine repair of spina bifida confers multiple advantages to infants, including:[2][3]
  • Surgery after birth is done in patients who did not underwent prenatal surgery but the prognosis is worse and there are more possible complications after surgery in comparison with the prenatal surgery. [3]

References

  1. Ciovîrnache M, Simionescu L, Ioaniţiu D (1990). "[A study of palmar flexion folds by the Perera-Kolski quantitative method in acromegaly]". Endocrinologie (in French). 28 (2): 57–62. PMID 2293328.
  2. 2.0 2.1 Tilles DS, Goldenheim PD, Johnson DC, Mendelson JH, Mello NK, Hales CA (April 1986). "Marijuana smoking as cause of reduction in single-breath carbon monoxide diffusing capacity". Am. J. Med. 80 (4): 601–6. PMID 3963040.
  3. 3.0 3.1 3.2 Bannur BB, Purandare GM (February 1969). "Microbial production of L-lysine". Hindustan Antibiot Bull. 11 (3): 191–205. PMID 4898641.

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