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This page provides a simple browsing interface for finding entities described by a property and a named value. Other available search interfaces include the page property search, and the ask query builder.
List of results
- WBR0291 + (Edema factor is an exotoxin of ''B. anthracis'', the bacteria responsible for anthrax. Edema factor has calmodulin (CaM)-activated adenylyl cyclase activity that increases the concentration of cyclic AMP (cAMP) to supraphysiological levels.)
- WBR0638 + (Elastin content is a property of tissue type and is not usually increased in scar tissue.)
- WBR0324 + (Enhancers are specific regions on DNA that bind to transcription factors and alter gene expression. They are located anywhere along or outside the transcribed DNA region.)
- WBR0796 + (Eosinophilic infiltration in the liver on biopsy is frequently seen in several conditions, such as autoimmune hepatitis and drug-induced liver injury. Nonetheless, liver eosinophilia is not diagnostic in either conditions.)
- WBR0879 + (Ependymoma is not associated with Parinaud syndrome. Classically ependymomas present with hydrocephalus.)
- WBR0774 + (Esophageal esophagitis is not associated with Plummer-Vinson syndrome.)
- WBR0160 + (Etoposide is a topoisomerase II inhibitor … Etoposide is a topoisomerase II inhibitor that causes DNA damage by inducing strand breaks. Etoposide is a cell-cycle-specific chemotherapeutic agent that acts primarily during S and G2 phases. It is indicated for a variety of solid tumors including small cell lung carcinoma and hematopoetic malignancies. Classically, administration of etoposide is associated with bone marrow suppression.s associated with bone marrow suppression.)
- WBR0749 + (Ewing's sarcoma is a common bone tumor of … Ewing's sarcoma is a common bone tumor of childhood. It appears in the diaphysis of long bones, in the pelvis, or scapula. On pathology, the tumor appears as small blue cells of malignant features with onion-skin appearance in bone. It is caused by a t(11,22) translocation. It is caused by a t(11,22) translocation.)
- WBR0784 + (Factor IX deficiency is seen in patients with Hemophilia A. Patients are at risk for hemarthrosis and heavy bleeding after trauma.)
- WBR284 + (Failure of migration of neural crest cells to the endocardial cushion is the most common congenital heart disease associated with Down syndrome.)
- WBR0692 + (Fatigue due to cancer treatment usually lasts for 6 months or longer. It is highly unlikely that fatigue as a result of cancer treatment presents 20 years after cancer treatment.)
- WBR1082 + (Fatigue will not cause an initial improvement and then worsening)
- WBR0745 + (Fava bean intake is associated with hemolysis in patients with G6PD deficiency.)
- WBR0449 + (Femoral nerve is commonly injured in pelvic fractures. In this case, the patient will be unable to flex the thigh or extend the leg. Trendelenburg sign would not be present.)
- WBR0726 + (Fenofibrate is indicated for dyslipidemia, especially hypertriglyceridemia. Gynecomastia is not a typical adverse effect of fenofibrate therapy.)
- WBR0013 + (Ferruginous bodies are one type of asbestos bodies that are characterized by clear central fibers surrounded by a golden brown iron-protein complex. They are associated with occupational asbestos exposure.)
- WBR0896 + (Fever may be managed with IV acetaminophen, but oral medications cannot be administered.)
- WBR0290 + (Fibrillin protein defects cause Marfan syndrome and Weill-Marchesani syndrome. Chediak-Higashi syndrome is not associated with fibrillin protein defects.)
- WBR0509 + (Finasteride is a selective inhibitor of 5-alpha-reductase used in the treatment of androgenetic alopecia.)
- WBR0252 + (Fluoroquinolones inhibit DNA gyrase (topoisomerase II) and topoisomerase IV.)
- WBR0156 + (Folic acid (vitamin B9) may be administere … Folic acid (vitamin B9) may be administered routinely with methotrexate to reduce nausea and mouth ulcers associated with methotrexate administration. Unlike leucovorin, folic acid cannot overcome methotrexate-induced inhibition of the dihydrofolate reductase enzyme and is not helpful in severe adverse events.d is not helpful in severe adverse events.)
- WBR249 + (For mild-to-moderate PCP, alternative ther … For mild-to-moderate PCP, alternative therapeutic regimens include either dapsone plus TMP, primaquine plus clindamycin, or atovaquone. Common triggers of hemolytic anemia include sulfonamides and other drugs such as chloroquine, isoniazid, nalidixic acid, nitrofurantoin, and primaquine.ixic acid, nitrofurantoin, and primaquine.)
- WBR0074 + (For mild-to-moderate disease, alternative … For mild-to-moderate disease, alternative therapeutic regimens include: dapsone plus TMP, primaquine plus clindamycin, and atovaquone. Common triggers of hemolytic anemia include sulfonamides and other drugs such as chloroquine, isoniazid, nalidixic acid, nitrofurantoin, and primaquine.ixic acid, nitrofurantoin, and primaquine.)
- WBR0790 + (Foscarnet is used in the treatment of CMV retinitis and although not very common, can cause electrolyte imbalances typically hypomagnesemia, hypocalcemia, and hypophosphatemia.)
- WBR0175 + (Frequently, patients with tropical sprue have inflammation of the entire small bowel. Large bowel inflammation is not typically involved in tropical sprue.)
- WBR0799 + (Fructose is a simple monosaccharide that is often found bonded to glucose to form the disaccharide sucrose. It is not a primary source of fuel for the brain during starvation.)
- WBR0543 + (GABA has no role in pupillary constriction. Although the oculomotor nerve is involved, due to the activation of receptors in the Edinger-Westphal nucleus, the activated receptors are of opioid type, not GABA.)
- WBR0590 + (GABA release is reduced following the reduction in subthalamic excitability.)
- WBR0808 + (GIP increases insulin secretion, decreases gastric H<sup>+</sup>, and decreases GI motility.)
- WBR0936 + (GLUT5 is a fructose transporter expressed on the apical border of enterocytes in the small intestine. It does not translocate to the cell membrane with exercise.)
- WBR1076 + (Ganciclovir is the drug of choice for treatment of CMV retinitis . Since steroids increase the risk of CMV retinitis they are not indicated here. As a result ganciclovir with steroids is not the correct answer.)
- WBR0318 + (Gaucher's disease, a lysosomal storage disease, is characterized by hepatomegaly and aseptic necrosis of the femur. On pathology, Gaucher's cells ("crumpled tissue paper" macrophages) are observed.)
- WBR0150 + (Gene silencing is an epigenetic regulation of gene expression, where chromosomal DNA expression is shut down. It is most often achieved by methylation of the gene promoter. An example of a disorder caused by gene silencing is Prader-Willi syndrome.)
- WBR0102 + (Generalized tissue extensibility and fragility among EDS patients may be clinically evident by the presence of umbilical, inguinal, or incisional herniation.)
- WBR0477 + (Generally, a complete blood count (CBC) is … Generally, a complete blood count (CBC) is obtained for patients who are administered clozapine to monitor for leokopenia, granulocytopenia, and agranulocytosis by measurement of WBC and ANC levels. Although a CBC gives information about the hemoglobin levels, neither anemia nor polycythemia is the main concern following clozapine administration.oncern following clozapine administration.)
- WBR1019 + (Genital herpes is not a reportable sexually transmitted disease.)
- WBR0670 + (Given patient is unstable therefore, requires fluid resuscitation and further investigations.)
- WBR0660 + (Given the equation below, all variables are available to calculate the number needed to treat.)
- WBR0598 + (Golgi tendon organ (GTO) is an encapsulate … Golgi tendon organ (GTO) is an encapsulated collagen-containing cell located near the muscular-tendon junction of extrafusal muscles and is continuous with them. It signals muscle contraction and muscle tension, not muscle length (which is signaled by the muscle spindle). The terminals of GTO are compressed upon muscle contraction. Sustained muscle contraction causes a sustained afferent response. Adaptation to the twisting force is slow. Adaptation to the twisting force is slow.)
- WBR0691 + (Goodpasture's syndrome is a type II hypersensitivity. it is not a mixed hypersensitivity. An example of mixed hypersensitivity is hypersensitivity pneumonitis (type III and type IV).)
- WBR0321 + (Gout is caused by precipitation of monosodium urate crystals (MSU) in joints. It is a common complication of hyperuricemia.)
- WBR0555 + (HDL increases insulin secretion through AMP-activated protein kinase in skeletal muscle, thus, mediating glucose metabolism especially among patients with type 2 diabetes.)
- WBR0559 + (HIV patients with CD4 < 50 cells/mL may develop cryptococcal meningitis, CMV retinitis, and disseminated mycobacterium avium complex (MAC). HIV patients with CD4 < 50 cells/mL require once-weekly azythromycin against MAC.)
- WBR0891 + (HIV-associated dementia, a.k.a. Aids Demen … HIV-associated dementia, a.k.a. Aids Dementia Complex (ADC) is a metabolic encephalopathy induced by HIV infection and fueled by immune activation of brain macrophages and microglia. These cells are actively infected with HIV and secrete neurotoxins of both host and viral origin. The essential features are disabling cognitive impairment accompanied by motor dysfunction, speech problems and behavioral change. Cognitive impairment is characterized by mental slowness, trouble with memory and poor concentration. Motor symptoms include a loss of fine motor control leading to clumsiness, poor balance and tremors. Behavioral changes may include apathy, lethargy and diminished emotional responses and spontaneity. Histopathologically, it is identified by the infiltration of monocytes and macrophages into the central nervous system (CNS), gliosis, pallor of myelin sheaths, abnormalities of dendritic processes and neuronal apoptosis. ADC typically occurs after years of HIV infection and is associated with low CD4+ T cell levels and high plasma viral loads. It is sometimes seen as the first sign of the onset of AIDS. HAART may not only prevent or delay the onset of ADC in people with HIV infection; it can also improve mental function in people who already have ADC.</br>This is an example of an irreversible cause of dementia.mple of an irreversible cause of dementia.)
- WBR1119 + (HPV DNA testing is done in patients with ASC-US for > 25 years of age.)
- WBR0537 + (HR increases following ketamine infusion.)
- WBR1103 + (Haloperidol is a high potency typical anti … Haloperidol is a high potency typical antipsychotic whose mechanism of action involves blocking dopamine D2 receptors. Haloperidol toxicity is typically manifested as extrapyramidal side effects, including tardive dyskinesia. Haloperidol is not associated with QT interval prolongation. associated with QT interval prolongation.)
- WBR0493 + (Hashimoto's disease is a type IV hypersensitivity disorder.)
- WBR0142 + (Hashimoto's thyroiditis does not usually increase the risk of developing anaplastic carcinoma of the thyroid. These tumors carry a poor prognosis and tend to occur in older patients.)
- WBR0674 + (Heart, kidney, and spleen undergo white (pale or anemic) infarction.)