Solid and pseudopapillary epithelial neoplasm

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Solid and pseudopapillary epithelial neoplasm (SPEN) accounts for approximately 1% of pancreatic neoplasms. The high incidence in young women (mean, 24 years old) is especially noteworthy (Daughter tumor). Distinctive clinical features include eosinophilia and polyarthralgia. It is a low-grade malignancy. Resection is usually curative.

The imaging findings are,

• Can be solid, but they often present as thick-walled cysts on CT and sonography.
• Attenuation is high when hemorrhage occurs.
• CT will show peripheral or central stippled calcification in some lesions.
• Tumor vascularity is moderate

CT and PET image demonstrate a solid and pseudopapillary epithelial neoplasm in a teenage female

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