Postpartum thyroiditis epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sunny Kumar MD [2]

Overview

In 2012, the incidence of postpartum thyroiditis "PPT" was estimated to be 1600 to 18200 cases per 100,000 women. Incidence of PPT increase in patients with type 1 DM up to 25000 per 100,000 women. In 2012, the prevalence of PPT was estimated to be from 1000 to 20000, with a mean prevalence of 5000 cases per 100,000 women. PPT occurs in women of child bearing age. PPT usually affects individuals of the Mediterranean and Caucasian population race. Mongolian race is usually less affected with PPT. The majority of PPT cases are reported in Europe and Japan.

Epidemiology and Demographics

The epidemiology and demographics of postpartum thyroiditis is as follows:[1][2]

Incidence

  • In 2012, the incidence of PPT was estimated to be 1600 to 18200 cases per 100,000 women.
  • Incidence of PPT increase with patients having type 1 DM up to 25000 per 100,000 women.
  • Incidence of PPT increase with subsequent pregnancies.
  • Incidence of PPT increase with postive TPO antibodies and subsequent pregnancies to approximately 70000 cases per 100,000 women.
  • In 2000, the incidence of PPT was established to be approximately 7800 cases per 100,000 Mediterranean population.

Prevalence

  • In 2012, the prevalence of PPT was estimated to be from 1000 to 20000, with a mean prevalence of 5000 cases per 100,000 women.

Case-fatality rate

  • There is no data to suggest the case fatality rate of postpartum thyroiditis.

Age

  • PPT occurs in women in child bearing age.

Race

  • PPT usually affects individuals of the Mediterranean and Caucasians population race.
  • Mongolian race is usually less effected.

Region

  • The majority of PPT cases are reported in Europe and Japan.

Developed Countries

  • In USA, 9000 cases per 100,000 women have been reported to have PPT.
  • In Britain, 16700 cases per 100,000 women have been reported to have PPT.
  • In Italy, 8700 cases per 100,000 women have been reported to have PPT.

Developing Countries

  • In India, 7000 cases per 100,000 women have been reported to have PPT.
  • In Japan, 5300 to 21000 cases per 100,000 women have been reported to have PPT.
  • In Thailand, 1100 cases per 100,000 women have been reported to have PPT.

References

  1. Amino N, Tada H, Hidaka Y (1999). "Postpartum autoimmune thyroid syndrome: a model of aggravation of autoimmune disease". Thyroid. 9 (7): 705–13. doi:10.1089/thy.1999.9.705. PMID 10447018.
  2. Lazarus JH (1992). "Postpartum thyroid dysfunction". Thyroid. 2 (1): 81. doi:10.1089/thy.1992.2.81. PMID 1525572.

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