Porphyria physical examination

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

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Physical Examination

Appearance

The patient is dehydrated.

Vitals

• Tachycardia
• Hypertension

Skin

• Dry skin - because of dehydration
• Yellow discoloration skin may be seen - jaundice

Extremities

• Reddish appearance of fingernails in cutaneous porphyrias - due to accumulation of heme precursors.

Neurologic

• Seizures
• Clinical depression
• Paranoia