Plexiform neurofibroma

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A plexiform neurofibroma is a tumor of the peripheral nerves which is common in individuals with neurofibromatosis type I, and indeed is diagnostic of that condition. The tumor occurs when Schwann cells multiply out of control within the nerve sheath. While typically benign, the tumor occasionally may become malignant. The tumors are often painful or disfiguring and may lead to disability.

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