Pleural empyema epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Prince Tano Djan, BSc, MBChB [2]

Overview

The incidence and prevalence of empyema has been increasing over the past 15 years. More than 40% of patients have preexisting comorbidities.[1] There have been a 26% increase in age and sex-standardized incidence rate from 8.7 per 100,000 person-years in 1997 to 11.8 per 100,000 person in 2011.[1] This increment is most notably among older people aged ≥ 80 years (87.3% [from 20.4 per 100,000 in 1997 to 38.2 per 100,000 in 2011]) compared with people aged 40 to 64 years (27.8% [from 10.7 per 100,000 in 1997 to 12.6 per 100,000 in 2011]).[1] Men are more commonly affected with empyema than women. The male to female ratio is approximately 1.7- to 3.1-fold higher in men than in women.[1] The rate of patients with empyema requiring hospitalization appear to be increasing in western populations, however updated population-based data are scanty. The few available data on adult empyema have reported increase between 30% and 97% over the past 15 years in the United States and Canada.[1][2] There is however a decreasing trend in the median days of hospital stay from 22 days 17 days.[1]

Epidemiology and demographics

Incidence and prevalence

The incidence and prevalence of empyema has been increasing over the past 15 years. More than 40% of patients have preexisting comorbidities.[1]

There have been a 26% increase in age and sex-standardized incidence rate from 8.7 per 100,000 person-years in 1997 to 11.8 per 100,000 person-years in 2011.[1] This increment is most notably among older people aged ≥ 80 years (87.3% [from 20.4 per 100,000 in 1997 to 38.2 per 100,000 in 2011]) compared with people aged 40 to 64 years (27.8% [from 10.7 per 100,000 in 1997 to 12.6 per 100,000 in 2011])[1]

Age

Empyema is increases with increasing age. Elderly patients >64 years are most commonly affected.[1]

Gender

Men are more commonly affected with empyema than women. The male to female ratio is approximately 1.7- to 3.1-fold higher in men than in women.[1]

Developed and developing countries

The rate of patients with empyema requiring hospitalization appears to be increasing in western populations, however updated population-based data are scanty. The few available data on adult empyema have reported increases between 30% and 97% over the past 15 years in the United States and Canada.[1][2]

There is however a decreasing trend in the median days of hospital stay from 22 days 17 days.[1]

References

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 Søgaard M, Nielsen RB, Nørgaard M, Kornum JB, Schønheyder HC, Thomsen RW (2014). "Incidence, length of stay, and prognosis of hospitalized patients with pleural empyema: a 15-year Danish nationwide cohort study". Chest. 145 (1): 189–92. doi:10.1378/chest.13-1912. PMID 24394842.
  2. 2.0 2.1 Farjah F, Symons RG, Krishnadasan B, Wood DE, Flum DR (2007). "Management of pleural space infections: a population-based analysis". J Thorac Cardiovasc Surg. 133 (2): 346–51. doi:10.1016/j.jtcvs.2006.09.038. PMID 17258562.

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