Pharyngitis pathophysiology

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Venkata Sivakrishna Kumar Pulivarthi M.B.B.S [2]Delband Yekta Moazami, M.D.[3]


The pathogenesis of the sore throat due to pharyngitis is poorly understood. The pharynx is often the first site of infection for many contagious diseases such as pharyngitis because pathogens such as viruses and bacteria often settle in the nasopharynx through inhalation or through droplets. Viral pharyngitis usually transmits from person to person through direct touch or through droplets transmission. The foreign invader reproduces rapidly after settling on the nasopharynx. Generally, pharyngitis is a primary disease, but may be associated with systemic disorders such as the acute retroviral syndrome, or part of a more generalized upper respiratory tract infection.



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  5. Bennett, John (2015). Mandell, Douglas, and Bennett's principles and practice of infectious diseases. Philadelphia, PA: Elsevier/Saunders. ISBN 978-1455748013.
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  7. Murray RC, Chennupati SK (2012) Chronic streptococcal and non-streptococcal pharyngitis. Infect Disord Drug Targets 12 (4):281-5. PMID: 22338589