PISRT1 (polled intersex syndrome regulated transcript 1) is a long non-coding RNA. It has been implicated in the polled intersex (PIS) mutation in goats.[1] It has been shown not to be involved in sex determination in the rodent Ellobius lutescens and in dogs, and is unlikely to be involved in sex-specific gonad differentiation in mice.[2][3][4]
↑Baumstark A, Hameister H, Hakhverdyan M, Bakloushinskaya I, Just W (April 2005). "Characterization of Pisrt1/Foxl2 in Ellobius lutescens and exclusion as sex-determining genes". Mamm. Genome. 16 (4): 281–9. doi:10.1007/s00335-004-2019-7. PMID15965789.
↑Kothapalli KS, Kirkness E, Natale LJ, Meyers-Wallen VN (December 2003). "Exclusion of PISRT1 as a candidate locus for canine Sry-negative XX sex reversal". Anim. Genet. 34 (6): 467–9. doi:10.1046/j.0268-9146.2003.01053.x. PMID14687082.
↑Loffler KA, Combes AN, Wilhelm D, Beverdam A, Bowles J, Koopman P (2005). "Pisrt1, a gene implicated in XX sex reversal, is expressed in gonads of both sexes during mouse development". Mol. Genet. Metab. 86 (1–2): 286–92. doi:10.1016/j.ymgme.2005.06.013. PMID16137905.
