Omega-6 fatty acid
Template:Fats Omega-6 fatty acids are fatty acids where the term "omega-6" signifies that the first double bond in the carbon backbone of the fatty acid, occurs in the omega minus 6 position; that is, the sixth carbon from the end of the fatty acid. See essential fatty acids for more detail on the naming system.
The biological effects of the ω-6 fatty acids are largely mediated by their interactions with the ω-3 fatty acids, see Essential fatty acid interactions for detail.
Linoleic acid (18:2), the shortest chain omega-6 fatty acid is an essential fatty acid. Arachidonic acid (20:4) is a physiologically significant n-6 fatty acid and is the precursor for prostaglandins and other physiologically active molecules.
Dietary sources of omega-6 fatty acids include:
- whole-grain breads
- most vegetable oils
- eggs and poultry
- baked goods.
Modern Western diets typically have ratios of omega-6 to omega-3 in excess of 10 to 1, some as high as 30 to 1. The optimal ratio is thought to be 4 to 1 or lower. 
List of omega-6 fatty acids
|Common name||Lipid name||Chemical name|
|Linoleic acid||18:2 (n-6)||9,12-octadecadienoic acid|
|Gamma-linolenic acid||18:3 (n-6)||6,9,12-octadecatrienoic acid|
|Eicosadienoic acid||20:2 (n-6)||11,14-eicosadienoic acid|
|Dihomo-gamma-linolenic acid||20:3 (n-6)||8,11,14-eicosatrienoic acid|
|Arachidonic acid||20:4 (n-6)||5,8,11,14-eicosatetraenoic acid|
|Docosadienoic acid||22:2 (n-6)||13,16-docosadienoic acid|
|Adrenic acid||22:4 (n-6)||7,10,13,16-docosatetraenoic acid|
|Docosapentaenoic acid||22:5 (n-6)||4,7,10,13,16-docosapentaenoic acid|
|Calendic acid||18:3 (n-6)||8E,10E,12Z-octadecatrienoic acid|
Some medical research has suggested that excessive levels of omega-6 acids, relative to Omega-3 fatty acids, may increase the probability of a number of diseases and depression. However, more recently, the Cochrane Collaboration reported only a decrease in myocardial infarction.
-  Omega-6 fatty acids cause prostate tumor cell growth in culture
-  Omega-6 fatty acids linked to major depression
- ↑ Simopoulos AP (2002). "The importance of the ratio of omega-6/omega-3 essential fatty acids". Biomed Pharmacother. 56 (8): 365–79. PMID 12442909.
- ↑ Hooper L, Al-Khudairy L, Abdelhamid AS, Rees K, Brainard JS, Brown TJ; et al. (2018). "Omega-6 fats for the primary and secondary prevention of cardiovascular disease". Cochrane Database Syst Rev. 11: CD011094. doi:10.1002/14651858.CD011094.pub4. PMID 30488422.
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