Metaraminol

Metaraminol

Clinical data
Pregnancy category	AU: C US: C (Risk not ruled out)
Routes of administration	Intravenous
ATC code	C01CA09 (WHO)
Legal status
Legal status	UK: POM (Prescription only)
Pharmacokinetic data
Bioavailability	n/a
Protein binding	~45%
Metabolism	Hepatic
Identifiers
IUPAC name 3-[(1R,2S)-2-amino-1-hydroxy-propyl]phenol
CAS Number	54-49-9
PubChem CID	5906
DrugBank	APRD00555
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C9H13NO2
Molar mass	167.205 g/mol

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Experimental / Informatics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Metaraminol (INN, trade name Aramine) is a potent sympathomimetic amine used in the prevention and treatment of hypotension, particularly as a complication of anesthesia. It is an α₁-adrenergic receptor agonist with some β effect.

Metaraminol is also used in the treatment of priapism. Although not approved for this use, it appears to be effective.