Mestranol

Mestranol

Identifiers
IUPAC name (8S,9S,13S,14S,17S)-17-ethynyl-3-methoxy- 13-methyl-7,8,9,11,12,14,15,16-octahydro-6H- cyclopenta[a]phenanthren-17-ol
CAS Number	72-33-3
PubChem CID	6291
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C21H26O2
Molar mass	310.43 g/mol

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Mestranol is the 3-methyl ether of ethinylestradiol. It was the estrogen used in many of the first oral contraceptives.

It is a biologically inactive prodrug of ethinylestradiol to which it is demethylated in the liver with a conversion efficiency of 70% (50 µg of mestranol is pharmacokinetically bioequivalent to 35 µg of ethinylestradiol).