Membranous glomerulonephritis other diagnostic studies
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Syed Ahsan Hussain, M.D.[2]
Overview
The other diagnostic study is the renal biopsy which is also confirmatory test. Its microscopic finding is the thickness of glomerular basement membrane.
Other Diagnostic Studies
Kidney biopsy
- The patients with compromised renal functions are indicated for biopsy [1][2][3]
- The biopsy is indicated, untill contraindicated if the PLA2R is negative.
For more information in microscopic findings on kidney biopsy, click here.
References
- ↑ Ryan MS, Satoskar AA, Nadasdy GM, Brodsky SV, Hemminger JA, Nadasdy T (June 2016). "Phospholipase A2 receptor staining is absent in many kidney biopsies with early-stage membranous glomerulonephritis". Kidney Int. 89 (6): 1402–3. doi:10.1016/j.kint.2015.12.057. PMID 27181782.
- ↑ Hofstra JM, Debiec H, Short CD, Pellé T, Kleta R, Mathieson PW, Ronco P, Brenchley PE, Wetzels JF (October 2012). "Antiphospholipase A2 receptor antibody titer and subclass in idiopathic membranous nephropathy". J. Am. Soc. Nephrol. 23 (10): 1735–43. doi:10.1681/ASN.2012030242. PMC 3458465. PMID 22956816.
- ↑ Hofstra JM, Wetzels JF (June 2014). "Phospholipase A2 receptor antibodies in membranous nephropathy: unresolved issues". J. Am. Soc. Nephrol. 25 (6): 1137–9. doi:10.1681/ASN.2014010091. PMC 4033386. PMID 24610931.