Major or mild neurocognitive disorder due to prion disease

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]

Major or Mild Neurocognitive Disorder Due to Prion Disease

DSM-V Diagnostic Criteria for Major or Mild Neurocognitive Disorder Due to Prion Disease

“

A.The criteria are met for major or mild neurocognitive disorder. AND B.There is insidious onset, and rapid progression of impairment is common. AND C.There are motor features of prion disease, such as myoclonus or ataxia, or biomarker evidence. AND D.The neurocognitive disorder is not attributable to another medical condition and is not better expiated by another mental disorder.

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Epidemiology and Demographics

Prevalence

The prevalence of major or mild neurocognitive disorder due to prion disease is unknown.

Risk Factors

• Anecdotal
• Corneal transplantation
• Human growth factor injection

Differential Diagnosis

• Other major neurocognitive disorders