Magnesium hydroxide

Magnesium hydroxide
Adult Indications & Dosage
Pediatric Indications & Dosage
Contraindications
Warnings & Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Administration & Monitoring
Overdosage
Pharmacology
Clinical Studies
How Supplied
Images
Patient Counseling Information
Precautions with Alcohol
Brand Names
Look-Alike Names

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

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Overview

Magnesium hydroxide is an antacid that is FDA approved for the treatment of saline laxative and antacid. Common adverse reactions include hypermagnesemia.

Adult Indications and Dosage

FDA-Labeled Indications and Dosage (Adult)

Laxative

• Relieves occasional constipation; generally produces a bowel movement in 1/2 to 6 hours.
• Drink a full glass (8 ounces) of liquid with each dose
• Adults and children 12 years and older: 2 to 4 tablespoons
• Adults and children 12 years and older: 1 to 3 teaspoons with water, up to 4 times daily

Antacid

• Relieves heartburn, sour stomach & acid indigestion.
• Do not take more than 12 teaspoons in 24 hours
• Do not use maximum dosage for more than 2 weeks

Off-Label Use and Dosage (Adult)

Guideline-Supported Use

• Indigestion

Non–Guideline-Supported Use

• Calcium renal calculus; Prophylaxis
• Constipation.

Pediatric Indications and Dosage

FDA-Labeled Indications and Dosage (Pediatric)

Laxative

• Children 6 to under 12 years: 1 to 2 tablespoons.
• Children 2 to under 6 years: 1 to 3 teaspoons.

Off-Label Use and Dosage (Pediatric)

Guideline-Supported Use

• Indigestion
• Constipation.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Magnesium hydroxide in pediatric patients.

Contraindications

There is limited information regarding Magnesium hydroxide Contraindications in the drug label.

Warnings

Use caution if the following conditions coexist.

• Kidney disease.
• A magnesium-restricted diet.
• Stomach pain, nausea or vomiting.
• A sudden change in bowel habits that lasts over 2 weeks.
• Ask a doctor or pharmacist before use if you are taking any other drug.
• Antacids may interact with certain prescription drugs ° laxatives may affect how other drugs work, so should be taken 2 or more hours before or after other drugs.
• When using this product as an antacid, it may have a laxative effect.
• Stop use and ask a doctor if have following symptoms.

• Rectal bleeding or no bowel movement after using this product. These could be signs of a serious condition
• If pregnant or breast-feeding, ask a health professional before use.

Adverse Reactions

Clinical Trials Experience

There is limited information regarding Magnesium hydroxide Clinical Trials Experience in the drug label.

Postmarketing Experience

Endocrine metabolic

Hypermagnesemia

Drug Interactions

There is limited information regarding Magnesium hydroxide Drug Interactions in the drug label.

Use in Specific Populations

Pregnancy

Pregnancy Category (FDA): D There is no FDA guidance on usage of Magnesium hydroxide in women who are pregnant.
Pregnancy Category (AUS):

• Australian Drug Evaluation Committee (ADEC) Pregnancy Category

There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Magnesium hydroxide in women who are pregnant.

Labor and Delivery

There is no FDA guidance on use of Magnesium hydroxide during labor and delivery.

Nursing Mothers

There is no FDA guidance on the use of Magnesium hydroxide with respect to nursing mothers.

Pediatric Use

There is no FDA guidance on the use of Magnesium hydroxide with respect to pediatric patients.

Geriatic Use

There is no FDA guidance on the use of Magnesium hydroxide with respect to geriatric patients.

Gender

There is no FDA guidance on the use of Magnesium hydroxide with respect to specific gender populations.

Race

There is no FDA guidance on the use of Magnesium hydroxide with respect to specific racial populations.

Renal Impairment

There is no FDA guidance on the use of Magnesium hydroxide in patients with renal impairment.

Hepatic Impairment

There is no FDA guidance on the use of Magnesium hydroxide in patients with hepatic impairment.

Females of Reproductive Potential and Males

There is no FDA guidance on the use of Magnesium hydroxide in women of reproductive potentials and males.

Immunocompromised Patients

There is no FDA guidance one the use of Magnesium hydroxide in patients who are immunocompromised.

Administration and Monitoring

Administration

• Oral

Monitoring

There is limited information regarding Monitoring of Magnesium hydroxide in the drug label.

IV Compatibility

There is limited information regarding IV Compatibility of Magnesium hydroxide in the drug label.

Overdosage

There is limited information regarding Magnesium hydroxide overdosage. If you suspect drug poisoning or overdose, please contact the National Poison Help hotline (1-800-222-1222) immediately.

Pharmacology

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Template:Chembox header2 | Magnesium hydroxide
Identifiers
CAS Number	1309-42-8 Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:6637 Y
ChEMBL	ChEMBL1200718 N
ChemSpider	14107 Y
ECHA InfoCard
PubChem CID	14791
UNII	NBZ3QY004S Y
InChI InChI=1S/Mg.2H2O/h;2*1H2/q+2;;/p-2 Y Key: VTHJTEIRLNZDEV-UHFFFAOYSA-L Y InChI=1/Mg.2H2O/h;2*1H2/q+2;;/p-2 Key: VTHJTEIRLNZDEV-NUQVWONBAW
SMILES [Mg+2].[OH-].[OH-]
Properties
Chemical formula	Mg(OH)2
Molar mass	58.3197 g/mol
Hazards
Related compounds
Template:Chembox header2 | Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

Mechanism of Action

There is limited information regarding Magnesium hydroxide Mechanism of Action in the drug label.

Structure

There is limited information regarding Magnesium hydroxide Structure in the drug label.

Pharmacodynamics

There is limited information regarding Pharmacodynamics of Magnesium hydroxide in the drug label.

Pharmacokinetics

There is limited information regarding Pharmacokinetics of Magnesium hydroxide in the drug label.

Nonclinical Toxicology

There is limited information regarding Nonclinical Toxicology of Magnesium hydroxide in the drug label.

Clinical Studies

There is limited information regarding Clinical Studies of Magnesium hydroxide in the drug label.

How Supplied

• Each 5 mL teaspoon contains: magnesium 165mg and sodium 2 mg

Storage

• Store at room temperature
• Protect from freezing

Images

Drug Images

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Package and Label Display Panel

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Patient Counseling Information

Laxative

• Shake well before using
• Drink a full glass (8 ounces) of liquid with each dose
• May be taken as a single or divided dose
• Adults and children 12 years and older: 2 to 4 tablespoons
• Children 6 to under 12 years: 1 to 2 tablespoons
• Children 2 to under 6 years: 1 to 3 teaspoons
• Children under 2 years: ask a doctor

Antacid

• Do not take more than 12 teaspoons in 24 hours
• Do not use maximum dosage for more than 2 weeks
• Adults and children 12 years and older: 1 to 3 teaspoons with water, up to 4 times daily
• Children under 12 years: ask a doctor

Precautions with Alcohol

• Alcohol-Magnesium hydroxide interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

Brand Names

• MAGNESIUM HYDROXIDE ®

Look-Alike Drug Names

There is limited information regarding Magnesium hydroxide Look-Alike Drug Names in the drug label.

Drug Shortage Status

Price

References

The contents of this FDA label are provided by the National Library of Medicine.

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