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ICD-10 Q38.2
ICD-9 529.8
OMIM 153630
DiseasesDB 7689
MeSH D008260

WikiDoc Resources for Macroglossia


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Evidence Based Medicine

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Clinical Trials

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US National Guidelines Clearinghouse on Macroglossia

NICE Guidance on Macroglossia


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List of terms related to Macroglossia

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Carlos A Lopez, M.D. [2]


The common causes of macroglossia include acromegaly, amyloidosis, beckwith-Wiedemann syndrome, congenital hypothyroidism and down syndrome.


Life Threatening Causes

Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.

Common Causes

Causes by Organ System

Cardiovascular Cardiac amyloidosis
Chemical / poisoning No underlying causes
Dermatologic Hemangioma
Drug Side Effect Angioedema
Ear Nose Throat Acromegaly
Endocrine Acromegaly, congenital hypothyroidism, growth hormone secreting pituitary adenoma, hypothyroidism
Environmental No underlying causes
Gastroenterologic No underlying causes
Genetic Alpha-mannosidosis, Beckwith-Wiedemann syndrome, chromosome 12p tetrasomy syndrome, chromosome 9q deletion syndrome, congenital micrognathia, down syndrome, gM1 gangliosidoses, gM3 gangliosidoses, glycogen storage disease, Hunter syndrome, Hurler syndrome, Limb-girdle muscular dystrophy, lymphoma, monoclonal gammopathy of undetermined significance, I-cell disease, omphalocele, Smith-Lemli-Opitz syndrome, Pompe disease, Potocki-Lupski syndrome, Simpson-Golabi-Behmel syndrome, tongue cancer
Hematologic Multiple myeloma, monoclonal gammopathy of undetermined significance, lymphoma, down syndrome
Iatrogenic No underlying causes
Infectious Disease No underlying causes
Musculoskeletal / Ortho Acromegaly, Beckwith-Wiedemann syndrome, congenital hypothyroidism, cystic hygroma, Limb-girdle muscular dystrophy, multiple myeloma, sleep apnea, Simpson-Golabi-Behmel syndrome, Beckwith-Wiedemann syndrome, tongue cancer
Neurologic Neurofibromatosis
Nutritional / Metabolic Cardiac amyloidosis, amyloidosis, gM1 gangliosidoses, gM3 gangliosidoses, Hunter syndrome, immunoglobulin light chain amyloidosis, I-cell disease, Pompe disease, Potocki-Lupski syndrome
Obstetric/Gynecologic No underlying causes
Oncologic Hemangioma
Ophthalmologic No underlying causes
Overdose / Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary No underlying causes
Renal / Electrolyte No underlying causes
Rheum / Immune / Allergy Angioedema
Sexual No underlying causes
Trauma No underlying causes
Urologic No underlying causes
Miscellaneous Sleep apnea

Causes in Alphabetical Order

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Template:Congenital malformations and deformations of digestive system

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