MINE-R regimen

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]

Synonyms and keywords: Mesna-Ifosfamide-Novantrone-Etoposide-Rituximab Regimen; MINE-R Regimen

Overview

MINE-R regimen refers to a regimen consisting of mesna, ifosfamide, mitoxantrone, etoposide, and rituximab used to treat relapsed or refractory Hodgkin's lymphoma and non-Hodgkin's lymphoma.[1]

Regimen

MMesna

IIfosfamide

NMitoxantrone (Novantrone)

EEtoposide

RRituximab

Indications

Hodgkin's lymphoma and non-Hodgkin's lymphoma[1]

References

  1. 1.0 1.1 Rehwald U, Schulz H, Reiser M, Sieber M, Staak JO, Morschhauser F; et al. (2003). "Treatment of relapsed CD20+ Hodgkin lymphoma with the monoclonal antibody rituximab is effective and well tolerated: results of a phase 2 trial of the German Hodgkin Lymphoma Study Group". Blood. 101 (2): 420–4. doi:10.1182/blood.V101.2.420. PMID 12509381.