Linitis plastica upper GI endoscopy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]

Overview

On upper GI endoscopy, linitis plastica may show superficial ulcers and/or inflammation. On endoscopic ultrasound, abnormal thickening of the stomach wall is a characteristic finding.[1]

Upper GI Endoscopy

  • Esophagogastroduodenoscopy (EGD) or upper GI endoscopy with multiple deep tissue biopsies is performed to confirm the diagnosis of linitis plastica.[2]
  • Endoscopic ultrasound may be also performed to understand the depth of tumor invasion as well as spread of the disease to the adjacent structures.
    • A 10-20mm thickening of the submucosal layer is usually present.[1]

References

  1. 1.0 1.1 Gastric linitis plastica. Orphanet. http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=GB&Expert=36273 Accessed on December 9, 2015.
  2. Maeda E, Oryu M, Tani J, Miyoshi H, Morishita A, Yoneyama H; et al. (2015). "Characteristic waffle-like appearance of gastric linitis plastica: A case report". Oncol Lett. 9 (1): 262–264. doi:10.3892/ol.2014.2688. PMC 4246919. PMID 25435971.
  3. Mastoraki A, Papanikolaou IS, Sakorafas G, Safioleas M (2009). "Facing the challenge of managing linitis plastica--review of the literature". Hepatogastroenterology. 56 (96): 1773–8. PMID 20214236.


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