Josamycin

Josamycin

Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	J01FA07 (WHO)
Identifiers
IUPAC name (2S,3S,4R,6S) -6- {[(2R,3S,4R,5R,6S) -6- {[(4R,5S,6S,7R,9R,10R,11E,13E,16R) -4- (acetyloxy)-10-hydroxy-5-methoxy-9, 16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11, 13-dien-6-yl]oxy}-4-(dimethylamino)-5-hydroxy-2-methyloxan-3-yl]oxy}-4-hydroxy-2, 4-dimethyloxan-3-yl 3-methylbutanoate
CAS Number	16846-24-5 Y
PubChem CID	5284579
DrugBank	DB01321 Y
ChemSpider	4447629 Y
UNII	HV13HFS217
KEGG	D01235 Y
ChEBI	CHEBI:31739 N
ChEMBL	ChEMBL224436 N
PDB ligand	JOS (PDBe, RCSB PDB)
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C42H69NO15
Molar mass	827.995 g/mol
3D model (JSmol)	Interactive image
SMILES O=CC[C@H]3C[C@@H](C)[C@@H](O)/C=C/C=C/C[C@H](OC(=O)C[C@@H](OC(=O)C)C(OC)[C@H]3O[C@@H]2O[C@@H]([C@@H](O[C@@H]1O[C@H]([C@@H](OC(=O)CC(C)C)[C@](O)(C1)C)C)[C@H](N(C)C)[C@H]2O)C)C
InChI InChI=1S/C42H69NO15/c1-23(2)19-32(47)56-40-27(6)53-34(22-42(40,8)50)57-37-26(5)54-41(36(49)35(37)43(9)10)58-38-29(17-18-44)20-24(3)30(46)16-14-12-13-15-25(4)52-33(48)21-31(39(38)51-11)55-28(7)45/h12-14,16,18,23-27,29-31,34-41,46,49-50H,15,17,19-22H2,1-11H3/b13-12+,16-14+/t24-,25-,26-,27+,29+,30+,31-,34+,35-,36-,37-,38+,39?,40-,41+,42-/m1/s1 Y Key:XJSFLOJWULLJQS-HTYUZQQASA-N Y
NY (what is this?)  (verify)

WikiDoc Resources for Josamycin
Articles
Most recent articles on Josamycin Most cited articles on Josamycin Review articles on Josamycin Articles on Josamycin in N Eng J Med, Lancet, BMJ
Media
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Evidence Based Medicine
Cochrane Collaboration on Josamycin Bandolier on Josamycin TRIP on Josamycin
Clinical Trials
Ongoing Trials on Josamycin at Clinical Trials.gov Trial results on Josamycin Clinical Trials on Josamycin at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Josamycin NICE Guidance on Josamycin NHS PRODIGY Guidance FDA on Josamycin CDC on Josamycin
Books
Books on Josamycin
News
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Commentary
Blogs on Josamycin
Definitions
Definitions of Josamycin
Patient Resources / Community
Patient resources on Josamycin Discussion groups on Josamycin Patient Handouts on Josamycin Directions to Hospitals Treating Josamycin Risk calculators and risk factors for Josamycin
Healthcare Provider Resources
Symptoms of Josamycin Causes & Risk Factors for Josamycin Diagnostic studies for Josamycin Treatment of Josamycin
Continuing Medical Education (CME)
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International
Josamycin en Espanol Josamycin en Francais
Business
Josamycin in the Marketplace Patents on Josamycin
Experimental / Informatics
List of terms related to Josamycin

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Josamycin is a macrolide antibiotic. It is synthesized from strains of Streptomyces narbonensis var. josamyceticus var. nova

Currently sold in various countries.

Brand examples are:

Europe: Josalid, Josacine, Iosalide, Josamina. Russia: Wilprafen (Вильпрафен). Japan: Josamy.

Adverse effects

There has been a case report of oedema of the feet.