Headaches in children pathophysiology
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
It is thought that [disease name] is the result of / is mediated by / is produced by / is caused by either [hypothesis 1], [hypothesis 2], or [hypothesis 3].
[Pathogen name] is usually transmitted via the [transmission route] route to the human host.
Following transmission/ingestion, the [pathogen] uses the [entry site] to invade the [cell name] cell.
Pathophysiology
Physiology
The normal physiology of [name of process] can be understood as follows:
Pathogenesis
- It is understood that primary headache disorder is not due to an underlying disorder and secondary headache disorder is caused by either trauma[1], vascular[1], infections[2], inflammatory[3], structural[3], tumors[2], metabolic[1], epilepsy[3], or hypoxia[1].
Genetics
[Disease name] is transmitted in [mode of genetic transmission] pattern.
OR
Genes involved in the pathogenesis of [disease name] include:
- [Gene1]
- [Gene2]
- [Gene3]
OR
The development of [disease name] is the result of multiple genetic mutations such as:
- [Mutation 1]
- [Mutation 2]
- [Mutation 3]
Associated Conditions
Conditions associated with [disease name] include:
- [Condition 1]
- [Condition 2]
- [Condition 3]
Gross Pathology
On gross pathology, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].
Microscopic Pathology
On microscopic histopathological analysis, [feature1], [feature2], and [feature3] are characteristic findings of [disease name].
References
- ↑ 1.0 1.1 1.2 1.3 Kelly M, Strelzik J, Langdon R, DiSabella M (2018). "Pediatric headache: overview". Curr Opin Pediatr. 30 (6): 748–754. doi:10.1097/MOP.0000000000000688. PMID 30157045.
- ↑ 2.0 2.1 Ozge A, Termine C, Antonaci F, Natriashvili S, Guidetti V, Wöber-Bingöl C (2011). "Overview of diagnosis and management of paediatric headache. Part I: diagnosis". J Headache Pain. 12 (1): 13–23. doi:10.1007/s10194-011-0297-5. PMC 3056001. PMID 21359874.
- ↑ 3.0 3.1 3.2 Ahad R, Kossoff EH (2008). "Secondary intracranial causes for headaches in children". Curr Pain Headache Rep. 12 (5): 373–8. doi:10.1007/s11916-008-0063-9. PMID 18765144.