Fructose-bisphosphatase 2

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Identifiers
Aliases
External IDs	GeneCards: [1]
Orthologs
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a
Wikidata
View/Edit Human

Fructose-bisphosphatase 2 is a protein that in humans is encoded by the FBP2 gene.

Function

This gene encodes a gluconeogenesis regulatory enzyme which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. [provided by RefSeq, Jul 2008].

Further reading

• Rakus D, Maciaszczyk E, Wawrzycka D, Ułaszewski S, Eschrich K, Dzugaj A (October 2005). "The origin of the high sensitivity of muscle fructose 1,6-bisphosphatase towards AMP". FEBS Lett. 579 (25): 5577–81. doi:10.1016/j.febslet.2005.09.021. PMID 16213487.
• Gizak A, Maciaszczyk E, Dzugaj A, Eschrich K, Rakus D (July 2008). "Evolutionary conserved N-terminal region of human muscle fructose 1,6-bisphosphatase regulates its activity and the interaction with aldolase". Proteins. 72 (1): 209–16. doi:10.1002/prot.21909. PMID 18214967.
• Flachsbart F, Franke A, Kleindorp R, Caliebe A, Blanché H, Schreiber S, Nebel A (December 2010). "Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study". Mutat. Res. 694 (1–2): 13–9. doi:10.1016/j.mrfmmm.2010.08.006. PMID 20800603.
• Li H, Wang J, Xu H, Xing R, Pan Y, Li W, Cui J, Zhang H, Lu Y (September 2013). "Decreased fructose-1,6-bisphosphatase-2 expression promotes glycolysis and growth in gastric cancer cells". Mol. Cancer. 12 (1): 110. doi:10.1186/1476-4598-12-110. PMC 3849177. PMID 24063558.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.