Follicular thyroid cancer epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

The incidence of follicular thyroid cancer is estimated to be 0.82 per 100,000 individuals. Females are more commonly affected than males. The female to male ratio is approximately 3 to 1. The incidence of follicular thyroid cancer increases with age; the median age at diagnosis is 45 to 50 years.

Epidemiology and Demographics

Incidence

  • The incidence of follicular thyroid cancer in the USA is 0.82 per 100,000 person-years.
  • The incidence of follicular thyroid cancer is 1.06 per 100,000 woman-years.
  • The incidence of follicular thyroid cancer is 0.59 per 100,000 man-years.[1]
  • The American Cancer Society estimates:
    • Approximately 52,070 new cases of thyroid cancer in the US in the year 2019 with 73% and 27% of these cases in the female and male population, respectively.[2]

Prevalence

  • 9 of every 100 people with thyroid cancer have follicular thyroid cancer.[3]

Case Fatality Rate

  • Mortality rate of follicular thyroid cancer ranges from 5% to 15%.
  • The American Cancer Society estimates:
    • Approximately 2170 deaths from thyroid cancer in the US in the year 2019 with 53% of these deaths involving women and 47% involving men.[4]

Age

  • The median age at which follicular thyroid cancer is diagnosed is 45 to 50 years.

Gender

  • Follicular thyroid cancer is 3 times more common in female than in males.[5]

References

  1. Pacini, F.; Castagna, M. G.; Brilli, L.; Pentheroudakis, G. (2012). "Thyroid cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up". Annals of Oncology. 23 (suppl 7): vii110–vii119. doi:10.1093/annonc/mds230. ISSN 0923-7534.
  2. https://www.cancer.org/cancer/thyroid-cancer/about/key-statistics.html. Missing or empty |title= (help)
  3. Harach HR, Escalante DA, Onativia A, Lederer Outes J, Saravia Day E, Williams ED (January 1985). "Thyroid carcinoma and thyroiditis in an endemic goitre region before and after iodine prophylaxis". Acta Endocrinol. 108 (1): 55–60. doi:10.1530/acta.0.1080055. PMID 3969810.
  4. https://www.cancer.org/cancer/thyroid-cancer/about/key-statistics.html. Missing or empty |title= (help)
  5. Taccaliti, Augusto; Palmonella, Gioia; Silvetti, Francesca; Boscaro, Marco (2012). "Thyroid Neoplasm". doi:10.5772/37754.