Febrile neutropenia (patient information)

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Febrile Neutropenia

Overview

What are the symptoms?

What are the causes?

Who is at highest risk?

Diagnosis

When to seek urgent medical care?

Treatment options

Where to find medical care for febrile neutropenia?

Prevention

What to expect (Outlook/Prognosis)?

Possible complications

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Febrile neutropenia is a condition when a patient has a fever and when neutrophils in the blood are too low.

It is important to have a written/electronic febrile neutropenia management plan available if you are at risk and to make it easier to advocate for care in emergency situations. Talk to your doctor and find out if you are at risk and if having a management plan is important for you.

Who is at highest risk?

A neutrophil is a type of white blood cell that helps fight infection. Having too few neutrophils increases the risk of infection.

Diagnosis

Your diagnosis, stage, treatment, treatment response and certain patient characteristics are considered by your doctor when assessing risk of febrile neutropenia.

When to seek urgent medical care?

You should monitor your body temperature and other symptoms of infection. If you have a fever of 100.4°F or higher, you should go to the emergency room immediately.

Treatment options

A neutropenic fever is most often seen as a complication of chemotherapy, when the treatment suppresses the bone marrow (does not allow the bone marrow to make enough cells). Antibiotics are used to treat this, however, as more chemotherapy combinations are developed, new antibiotics are used and new infection risks are found. Treatment with an antifungal prophylactic may also be used.

Where to find medical care for febrile neutropenia?

You may be treated in a hospital or as an outpatient in a doctor’s office.

Prevention

According to the current American Society of Clinical Oncology (ASCO) guidelines, interventions such as footwear exchange, protected environments, respiratory or surgical masks, nutritional supplements and a “neutropenic” diet are not recommended to be followed since research has shown that there is lack of benefit to patients.

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