Familial mediterranean fever historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2]

Overview

Familial Mediterranean fever was first described in a Jewish schoolgirl by Janeway and Mosenthal in 1908. In 1955, Dr. Heller called this disorder familial Mediterranean fever, which refers to its high prevalence in this region and the key presenting feature of periodic fever. The disease was life-threatening before the introduction of colchicine in 1972.

Familial Mediterranean fever was first described in a Jewish schoolgirl by Janeway and Mosenthal in 1908.^[1]
In 1945, Dr. Siegal, an american allergy specialist, published a case report under the title of benign paroxysmal peritonitis and defined this disorder.^[2]
In 1948, Dr. Reimann, first used the term periodic fever.
In 1955, Dr. Heller called this disorder familial Mediterranean fever, which refers to its high prevalence in this region and the key presenting feature of periodic fever.^[3]
In 1997, MEFV mutations were first implicated in the parthenogenesis of familial Mediterranean fever.^[4]

The disease was life-threatening before the introduction of colchicine in 1972.^[5]

↑ Janeway, Theodore C. (1908). "AN UNUSUAL PAROXYSMAL SYNDROME, PROBABLY ALLIED TO RECURRENT VOMITING,". Archives of Internal Medicine. II (3): 214. doi:10.1001/archinte.1908.00050080016002. ISSN 0730-188X.
↑ Sohar E, Gafni J, Pras M, Heller H (August 1967). "Familial Mediterranean fever. A survey of 470 cases and review of the literature". Am. J. Med. 43 (2): 227–53. PMID 5340644.
↑ HELLER H, SOHAR E, PRAS M (1961). "Ethnic distribution and amyloidosis in familial Mediterranean fever (FMF)". Pathol Microbiol (Basel). 24: 718–23. PMID 13906231.
↑ "Ancient missense mutations in a new member of the RoRet gene family are likely to cause familial Mediterranean fever. The International FMF Consortium". Cell. 90 (4): 797–807. August 1997. PMID 9288758.
↑ Goldfinger SE (December 1972). "Colchicine for familial Mediterranean fever". N. Engl. J. Med. 287 (25): 1302. doi:10.1056/NEJM197212212872514. PMID 4636899.