Etamivan

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Etamivan
Clinical data
Trade names	Analepticon
ATC code	R07AB04 (WHO) ;
Identifiers
	IUPAC name N,N-diethyl-4-hydroxy-3-methoxybenzamide;
CAS Number	304-84-7;
PubChem CID	9363;
DrugBank	DB08989 ;
ChemSpider	8996;
UNII	M44O63YPV9;
KEGG	D04080 ;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C12H17NO3
Molar mass	223.268 g/mol
3D model (JSmol)	Interactive image;
	SMILES CCN(CC)C(=O)C1=CC(=C(C=C1)O)OC;
	InChI InChI=1S/C12H17NO3/c1-4-13(5-2)12(15)9-6-7-10(14)11(8-9)16-3/h6-8,14H,4-5H2,1-3H3; Key:BQJODPIMMWWMFC-UHFFFAOYSA-N;
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Etamivan (INN) or ethamivan (USAN), trade name Analepticon, is a respiratory stimulant drug^[1] related to nikethamide. It was mainly used in the treatment of barbiturate overdose^[2] and chronic obstructive pulmonary disease,^[3] but has now largely fallen into disuse.

↑ Hirsh K, Wang SC. Respiratory stimulant effects of ethamivan and picrotoxin. Journal of Pharmacology and Experimental Therapeutics. 1975 May;193(2):657-63.
↑ Wheeldon PJ, Perry AW. The use of ethamivan in the treatment of barbiturate poisoning. Canadian Medical Association Journal. 1963 Jul 6;89:20-2.
↑ Sproule BJ, Jans RL, Breitkreutz H, Mahon W. Effects of ethamivan in patients with chronic respiratory disease. Canadian Medical Association Journal. 1964 Dec 5;91:1203-8.