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Epi-lipoxins are the 5R-epimers of lipoxins. These nonclassic eicosanoids are formed in vivo, in the presence of aspirin.[1] They play a counter-regulatory role in inflammation, serving as a stop signal.[2]


  1. Clària J, Serhan CN (1995). "Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions". Proc. Natl. Acad. Sci. U.S.A. 92 (21): 9475–9. PMID 7568157. Retrieved 2007-11-01.
  2. Serhan CN (2001). "Lipoxins and aspirin-triggered 15-epi-lipoxins are endogenous components of antiinflammation: emergence of the counterregulatory side". Arch. Immunol. Ther. Exp. (Warsz.). 49 (3): 177–88. PMID 11478391. |access-date= requires |url= (help)


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