Dicyclomine (patient information)

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Why this medication is prescribed

Dicyclomine is used to treat the symptoms of irritable bowel syndrome. Dicyclomine is in a class of medications called anticholinergics. It relieves muscle spasms in the gastrointestinal tract by blocking the activity of a certain natural substance in the body.

How this medication should be used

Dicyclomine comes as a capsule, a tablet, and a syrup to take by mouth. It is usually taken four times a day. To help you remember to take dicyclomine, take it around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take dicyclomine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor will probably start you on a low dose of dicyclomine and gradually increase your dose.

Other uses for this medicine

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Special precautions

Before taking dicyclomine:

  • tell your doctor and pharmacist if you are allergic to dicyclomine or any other medications.
  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention any of the following: amantadine (Symmetrel); antacids; antidepressants such as amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil); antihistamines; diet pills; digoxin (Lanoxin); ipratropium (Atrovent); isosorbide (Imdur, Ismo, Isordil, others); medications for anxiety, asthma, glaucoma, irregular heartbeat, mental illness, motion sickness, Parkinson's disease, seizures, ulcers, or urinary problems; metoclopramide (Reglan); monoamine oxidase (MAO) inhibitors, including phenelzine (Nardil) and tranylcypromine (Parnate); narcotic pain relievers such as meperidine (Demerol); nitroglycerin (Nitro-Bid, Nitrostat, others); sedatives; sleeping pills; and tranquilizers. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you have or have ever had glaucoma; ulcerative colitis; an enlarged prostate (prostatic hyperplasia); difficulty urinating; esophageal reflux (heartburn); a blockage in the gastrointestinal tract; myasthenia gravis; high blood pressure; an overactive thyroid gland (hyperthyroidism); nerve disease (autonomic neuropathy); heart failure; rapid or pounding heartbeat; hiatal hernia; or liver, kidney, or heart disease.
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking dicyclomine, call your doctor. Do not breast-feed while taking this medication.
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking dicyclomine.
  • you should know that dicyclomine may make you drowsy or cause blurred vision. Do not drive a car or operate machinery until you know how this medication affects you.
  • remember that alcohol can add to the drowsiness caused by this medication.
  • you should know that dicyclomine reduces the body's ability to cool off by sweating. In very high temperatures, dicyclomine can cause fever and heat stroke.

Special dietary instructions

Unless your doctor tells you otherwise, continue your normal diet.

What to do if you forget a dose

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Side effects

Minor side effects

Dicyclomine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • dry mouth
  • upset stomach
  • vomiting
  • constipation
  • stomach pain
  • gas or bloating
  • loss of appetite
  • dizziness
  • tingling
  • headache
  • drowsiness
  • weakness
  • blurred vision
  • double vision
  • difficulty urinating

Severe side effects

Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:

  • hot, flushed, dry skin
  • confusion
  • forgetfulness
  • seeing things or hearing voices that do not exist (hallucinating)
  • unsteadiness
  • coma
  • anxiety
  • excessive tiredness
  • difficulty falling asleep or staying asleep
  • excitement
  • inappropriate mood
  • muscle weakness
  • rapid or pounding heartbeat
  • fainting
  • hives
  • skin rash
  • itching
  • difficulty breathing or swallowing

Dicyclomine may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/report.htm] or by phone [1-800-332-1088].

Storage conditions needed for this medication

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Symptoms of overdose may include:

  • headache
  • upset stomach
  • vomiting
  • blurred vision
  • dilated pupils
  • hot, dry skin
  • dizziness
  • dry mouth
  • difficulty swallowing
  • nervousness
  • excitement
  • seeing things or hearing voices that do not exist (hallucinating)

Other information

Keep all appointments with your doctor.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

Brand names

  • Bentyl®
  • Bentyl® Syrup