Constrictive pericarditis future or investigational therapies
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Constrictive Pericarditis Microchapters |
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Differentiating Constrictive Pericarditis from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hafiz M. Ahmed, M.D.[2]
Overview
There are no established future or investigational therapies specifically recommended for constrictive pericarditis in the 2025 ACC expert consensus statement. Current management emphasizes distinguishing inflammatory, potentially reversible constriction from chronic noninflammatory constriction, because this distinction guides anti-inflammatory therapy versus surgical pericardiectomy.
Future or Investigational Therapies
- No investigational drug therapy is currently established specifically for constrictive pericarditis.
- Future research may refine the role of multimodality imaging in identifying reversible inflammatory constriction and selecting patients for medical therapy versus pericardiectomy.
- Novel risk models and machine learning approaches have been developed for recurrent pericarditis flare prediction, but these are not established therapies for constrictive pericarditis.[1]
References
- ↑ Wang TKM, Klein AL, Cremer PC, Imazio M, Kohnstamm S, Luis SA, Mardigyan V, Mukherjee M, Ordovas K, Vakamudi S, Wohlford GF. 2025 Concise Clinical Guidance: An ACC Expert Consensus Statement on the Diagnosis and Management of Pericarditis: A Report of the American College of Cardiology Solution Set Oversight Committee. Journal of the American College of Cardiology. 2025;86(25):2691-2719. https://doi.org/10.1016/j.jacc.2025.05.023.