Chagas disease natural history

	Chagas disease Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Chagas disease from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Criteria
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
X-ray
Echocardiography and Ultrasound
CT scan
MRI
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Chagas disease natural history On the Web
Most recent articles
cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Chagas disease natural history All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Chagas disease natural history
CDC on Chagas disease natural history
Chagas disease natural history in the news
Blogs on Chagas disease natural history
Directions to Hospitals Treating Chagas disease
Risk calculators and risk factors for Chagas disease natural history

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]

Overview

Natural history

Complications

Complications of Chagas disease include:

Prognosis

An index for classification of patients who have Chagas' disease was published in the August 24, 2006 edition of the New England Journal of Medicine.^[1] Based on over 500 patients, this index includes clinical aspects, X-ray findings, EKG, echocardiography and Holter.

**Chagas' risk factors**
Risk factor	points
NYHA class III or IV	5
Cardiomegaly	5
Wall motion abnormalities	3
Non-sustained ventricular tachycardia	3
Low voltage on ECG	2
Male gender	2

Total points	Risk of death in 10 years
0–6	10%
7–11	40%
12–20	85%

References

↑ Rassi A Jr, Rassi A, Little W, Xavier S, Rassi S, Rassi A, Rassi G, Hasslocher-Moreno A, Sousa A, Scanavacca M (2006). "Development and validation of a risk score for predicting death in Chagas' heart disease". N Engl J Med. 355 (8): 799–808. PMID 16928995.

Template:WH Template:WS complications and prognosis

[1] Rassi A Jr, Rassi A, Little W, Xavier S, Rassi S, Rassi A, Rassi G, Hasslocher-Moreno A, Sousa A, Scanavacca M (2006). "Development and validation of a risk score for predicting death in Chagas' heart disease". N Engl J Med. 355 (8): 799–808. PMID 16928995.

[1]